Introduction: Success in pulp space therapy is gained after thorough biomechanical preparation and obturation of the root canal system. Case report: This clinical case describes the traditional root canal treatment of a rare root canal configuration of mandibular first molar with six root canals. A favourable outcome of endodontic treatment in teeth with abnormal morphology is less likely, if the clinician fails to recognize extra root canals through proper clinical and radiographic examination as well as use of dental operating microscope. Conclusion: Clinicians should use increased magnification and advanced diagnostic aids, to ensure identification and management of additional canals.