Radiotherapy of Vertebral Hemangiomas

Sakata, Koh‐ichi; Hareyama, Masato; Oouchi, Atsushi; Sido, Mitsuo; Nagakura, Hisayasu; Tamakawa, Mitsuharu; Akiba, Hidenari; Morita, Kazuo

doi:10.3109/02841869709001344

Cited by 40 publications

(14 citation statements)

References 19 publications

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“…9,[14][15][16]21,23,25 However, the significance and likelihood of radiographic changes in the spine are still disputed. 14,22 Predicting which lesions are most amenable to radiosurgical shrinkage should continue to be of ongoing interest for such vascular spinal lesions, as their extramedullary proximity to the spinal cord will be a major determinant of optimal SRS dosing when radiotherapy cannot achieve sufficient conformity.…”

Section: Discussionmentioning

confidence: 99%

CyberKnife stereotactic radiosurgery for the treatment of symptomatic vertebral hemangiomas: a single-institution experience

Zhang

Chen

Chang

et al. 2017

FOC

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OBJECTIVE Symptomatic vertebral hemangiomas (SVHs) are a very rare pathology that can present with persistent pain or neurological deficits that warrant surgical intervention. Given the relative rarity and difficulty in assessment, the authors sought to present a dedicated series of SVHs treated using stereotactic radiosurgery (SRS) to provide insight into clinical decision making. METHODS A retrospective review of a single institution's experience with hypofractionated radiosurgery for SVH from 2004 to 2011 was conducted to determine the clinical and radiographic outcomes following SRS treatment. The authors report and analyze the treatment course of 5 patients with 7 lesions, 2 of which were treated primarily by SRS. RESULTS Of the 5 patients studied, 4 presented with a chief complaint of pain refractory to conservative measures. Three patients reported dysesthesias, and 2 reported upper-extremity weakness. Following radiosurgery, 4 of 5 patients exhibited improvement in their primary symptoms (3 for pain and 1 for weakness), achieving a clinical response after a mean period of 1 year. In 2 cases there was 20%–40% reduction in lesion size in the most responsive dimension as noted on images. All treatments were well tolerated. CONCLUSIONS SRS for SVH is a safe and feasible treatment strategy, comparable to prior radiotherapy studies, and in select cases may successfully confer delayed decompressive effects. Additional investigation will determine future patient selection and how conformal SRS treatment can best be administered.

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Section: Discussionmentioning

confidence: 99%

CyberKnife stereotactic radiosurgery for the treatment of symptomatic vertebral hemangiomas: a single-institution experience

Zhang

Chen

Chang

et al. 2017

FOC

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“…However, 30%-50% of patients with paraparesis due to hemangiomatous neural compression either do not improve or deteriorate neurologically when treated with radiation alone. 16 Ethanol sclerotherapy has also been used to decrease epidural compression by intravascular obliteration of hemangiomas. However, limited applicability and significant morbidity have been associated with ethanol sclerotherapy for hemangiomas causing symptomatic epidural compression.…”

Section: Discussionmentioning

confidence: 99%

Transpedicular N-butyl cyanoacrylate–mediated percutaneous embolization of symptomatic vertebral hemangiomas

Yao

Malek

2013

SPI

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“…[17][18][19] Çalış-mamızda da ağrı tüm hastalarda ortak semptom olup, diğer çalışmalara benzer şekilde sırt ve belde fazlaydı. Spinal kord basısı varlığında motor disfonksiyon görü-lür.…”

Section: Discussionunclassified