Radiotherapy for Early Stage of Hodgkin’s Disease at Kuwait Cancer Control Center, Kuwait

Alshemmari, Salem; Al-Humood, Salah; Muralidharan, K.C.; Varghese, Vidhya

doi:10.1159/000063245

Cited by 1 publication

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References 17 publications

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“…Radiotherapy was used as a primary treatment method in 28 patients. This group has previously been described [7], in which KaplanMeier estimate of overall survival at 10 years was 100%. The relapse-free survival at 5 years was 100% and at 10 years 83%.…”

Section: Resultsmentioning

confidence: 92%

Hodgkin’s Disease: Kuwait Experience

Alshemmari

Al-Humood²,

Ameen³

et al. 2004

Med Princ Pract

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Objective: To describe histologic subtypes, clinical presentation and treatment outcome of Hodgkin’s lymphoma in Kuwait. Subjects and Method: Patients older than 15 years, diagnosed with Hodgkin’s lymphoma between 1980 and 1998, were included in this retrospective analysis. Data were collected using a standardized form that included demographics, histologic subtypes, clinical presentation, stage, extranodal involvement, treatment modality and follow-up. Histology reports were obtained from hospital records. Results: There were 83 (59%) males and 57 (41%) females. Dominant histologic subtypes were nodular sclerosis 65 (46.4%) and mixed cellularity 42 (30%). Constitutional symptoms were reported by 54 (38.6%) of the cases. Two thirds (64%) of the cases were advanced. Primary extranodular involvement included liver (8%), gastrointestinal tract (7%), lung and bone marrow (4% each). Disease-free survival according to treatment groups were: radiotherapy alone 100%, chemotherapy alone 88%, and combined modality 65%. The 5-year Kaplan-Meier estimates of overall disease-free survival was 84%. Conclusion: In the cohort of 137 patients with Hodgkin’s disease the treatment with combined radiotherapy and chemotherapy had a remarkable outcome. However, evaluation of long-term treatment complications is needed.

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Section: Resultsmentioning

confidence: 92%