Radiotherapy for advanced-stage aggressive non-Hodgkin lymphoma

Successful treatment of paraspinal/spinal epidural lymphoma by early intervention and local control with proton beam therapy

“…Ernie et al reported that radiotherapy has a modest benefit in terms of overall survival, event-free survival, and local control for patients with advanced-stage aggressive NHL in comparison with an observation policy. 5 In our case, periodic MRI evaluations revealed the remaining gadolinium enhanced lesion, which meant that the existence of a residual viable tumor could not be completely ruled out. Rahmouni et al previously reported the enhancement of residual gadolinium after treatment to be associated with a local relapse based on their experience of performing periodic MRI evaluations in 21 patients with mediastinal lymphoma.…”