Radiotherapy combined with surgery as treatment for advanced cercival cancer

Perches, R Díaz; Lobatón, Alfonso Torres; Garcia, Mario C.

doi:10.1016/0360-3016(83)90345-0

Cited by 4 publications

(3 citation statements)

References 4 publications

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“…The outcome in patients undergoing pelvic exenteration is dependent on the preoperative general condition of the patient, the magnitude of the operation performed, the completeness of excision of the tumor, and the presence or absence of vascular and lymphatic invasions by the tumor. We agree with others [3] that the current clinical staging is an inaccurate indicator of residual tumor volume and spread. Only a careful histopathologic examination can be of predictive value.…”

Section: Undeterminedsupporting

confidence: 91%

“…We agree with others [3] that the current clinical staging is an inaccurate indicator of residual tumor volume and spread. Only a careful histopathologic examination can be of predictive value.…”

Section: Undeterminedsupporting

confidence: 91%

“…Although advanced stages of carcinoma of the cervix have had a significant decline in most of the developed countries [l], mostly because of an increase in cytologic screening at routine gynecologic examinations, they continue to pose a problem of significant magnitude in Latin America [2,3]. Clinicians are often confronted with bulky primaries and/or recurrent cervical carcinomas that have involved other pelvic organs but with no evidence of extrapelvic disease.…”

Section: Introductionmentioning

confidence: 99%

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Pelvic exenteration for carcinoma of the cervix: Analysis of 252 cases

Cuevas

Torres

Garza

et al. 1988

Journal of Surgical Oncology

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We present the results of 252 pelvic exenterations for primary and recurrent carcinoma of the cervix at the Hospital General de Mexico, a tertiary-care institution for the indigent. Emphasis is placed on the morbidity and mortality of the procedure in relation to patient selection. In underdeveloped countries, where early detection of cervical cancer is a rare event, pelvic exenteration must continue in the armamentarium of physicians; it can be associated with gains in the quality of life, with long-term survival, with effective rehabilitation, and possibly with cures.

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Section: Undeterminedsupporting

confidence: 91%

Section: Undeterminedsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

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Pelvic exenteration for carcinoma of the cervix: Analysis of 252 cases

Cuevas

Torres

Garza

et al. 1988

Journal of Surgical Oncology

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Immunotherapy using the streptococcal preparation OK-432 for the treatment of uterine cervical cancer

1987

Cancer

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The effectiveness of immunotherapy using a streptococcal preparation, OK-432, was evaluated for cervical cancer. The 382 eligible patients were stratified by presence/absence of surgical operation and clinical stage, and then, in each stratum, were randomly divided into two groups: an O K 4 3 2 treatment group and a control treatment group. The 3-year recurrence-free rates of 221 patients in the O K 4 3 2 group and 161 patients in the control group were 71.9% and 58.6%. respectively. The intergroup difference was statistically significant (P < 0.05). Delayed skin reactions to phytohemaggultinin (PHA) and Su-polysaccharide extracted from Strepfococcus pyogenes Su-strain (Su-PS) and peripheral lymphocyte counts were reduced within two months after the initiation of therapy in both groups. The observed immunological changes were apparently reversed by 3 months after the start of the therapy in the O K 4 3 2 group, but this took at least one year in the control group, with significant intergroup differences at 6 and 12 months of the therapy (P < 0.01). These results indicate that O K 4 3 2 can be considered as one of the most effective and useful immunotherapeutic agents for cervical cancer.Cancer 609394-2402, 1987.N RECENT YEARS there has been an increasing aware-

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Contemporary Management of Cancer of the Cervix

Deppe¹,

Malviya²

1991

Clinical Perspectives in Obstetrics and Gynecology

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Radiotherapy combined with surgery as treatment for advanced cercival cancer

Cited by 4 publications

References 4 publications

Pelvic exenteration for carcinoma of the cervix: Analysis of 252 cases

Pelvic exenteration for carcinoma of the cervix: Analysis of 252 cases

Immunotherapy using the streptococcal preparation OK-432 for the treatment of uterine cervical cancer

Contemporary Management of Cancer of the Cervix

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