Radiotherapeutic management of vestibular schwannomas using size- and location-adapted fractionation regimens to maximize the therapeutic ratio

Persistent Oxidative Stress in Vestibular Schwannomas After Stereotactic Radiation Therapy

“…One possibility is that the portion of the tumor encompassed in the histopathology specimen represents areas of de novo tumor growth and did not include areas that were previously irradiated. VS control rates are uniformly good with IR therapy and some studies have even demonstrated varying degrees of VS regression following IR therapy in a subset of patients (19). However, in contrast to many malignant tumors, rather than inducing tumor regression, IR typically only arrests tumor growth in most responsive VSs(2).…”