Radiosynovectomy using yttrium-90, phosphorus-32 or rhenium-188 radiocolloids versus corticoid instillation for rheumatoid arthritis of the knee

Abstract

Therapeutic efficacy of RSO for RA of the knee applying either P-32, Re-188 or Y-90 provides comparable results. Pain relief by RSO is longer lasting as compared to corticosteroid instillation.

Internal radiotherapy of painful bone metastases

“…Radiolabeling of various agents with 188 Re provides a variety of different therapeutic options outside the bone pain palliation, e.g. treatment of liver metastases or primary liver cancer with labeling to lipoidal [176] or microsphere [177], treatment of arthritis with labeling to colloids [178]. Other therapeutic options included 188 Re-labeled antibodies for treatment of leukemia [179,180], or variety of 188 Re-labeled agents in intracoronary brachytherapy [181][182][183].…”

核医学放射性核素治疗的研究现状及前景

“…Radionuclide therapies are also used for the treatment of a variety of malignancies with 131 I, 90 Y, and 188 Re, polycythemia with 32 P, chronic joint disease with radiosynovectomy, and intravascular radiation therapy (Werner et al, 1957;Domnitz et al, 1960;Osgood, 1968;Silberstein, 1979;Hoefnagel et al, 1987;Chen et al, 1993;Deutsch et al, 1993;Parmentier and Gardet, 1994;Rhodes et al, 1996;Najean and Rain, 1997a;1997b;Tavintharan et al, 1997;Chen et al, 2001;Buchmann et al, 2002;Clunie and Fischer, 2003;Chang et al, 2005;Schneider et al, 2005;Das, 2007;Mortazavi et al, 2007;Turkmen et al, 2007;Ugur et al, 2008;Mumtaz et al, 2009;Schultz et al, 2009;Shamim et al, 2010;de la Corte-Rodriguez et al, 2011;Kucuk et al, 2011;Lacin et al, 2011;Liepe et al, 2011;Liepe, 2012). Table 2 summarises the most commonly used radiopharmaceuticals for targeted radionuclide therapy, including their targeting mechanism and clinical indications.…”

Radiosynoviorthesis in Therapy for Inflammatory Joint Disorders

“…5) [26]. Интенсивность боли определяется по 10-балльной визуальной аналого-вой шкале [27]. Для объективной оценки результатов лечения иссле-дуется поглощение РФП после терапии в мягкотканной фазе при сцинтиграфии.…”