Radionuclide angiographic assessment of global and segmental left ventricular function at rest and during exercise after coronary artery bypass graft surgery.

Abstract

SUMMARY Left ventricular ejection fraction (LVEF) was measured by radionuclide angiography at rest and during supine bicycle exercise before and 3 months after coronary artery bypass graft surgery (CABG) in 20 patients with chronic stable angina. The CORONARY artery bypass graft surgery (CABG) relieves the pain of myocardial ischemia and improves quality of life. 1 2 Whether surgical treatment of symptomatic coronary artery disease improves ventricular function and prolongs life is controversial.2 This study reports the effect of CABG on left ventricular (LV) function assessed by biplane quantitative radionuclide angiography at rest and during sprint maximal and graded submaximal exercise before and 3 months after surgery. Patients and MethodsThe 20 subjects of this study were drawn from the 34 patients admitted to hospital for elective coronary angiography over a 7-month period because of refractory angina pectoris. They had no noncoronary heart disease and consented to enter the study. All 3,-adrenergic blocking medication was withdrawn 48 hours before commencing measurements, and nitrates were withheld for at least 12 hours. Biplane right anterior oblique (RAO) gated first-pass and left anterior

Radionuclide Assessment of Left Ventricular Function after Coronary Bypass Surgery in Patients with Previous Myocardial Infarction

“…Previous myocardial infarction did not attenuate the improvement of ventricular function after surgery observed in patients with coronary artery disease [5,6], Although actually slightly increased in comparison with preoperative values, global EF was unchanged as in other studies carried out earlier [7][8][9][10] or later [11][12][13] after surgery. This finding is in agreement with other similar studies where left ventricular function was not extremely damaged before surgery [6,14,15]. Compared to the resting examination of left ventricular function, postex ercise radionuclide ventriculography has shown clear improvements in left ventricular wall motion as a benefit from aortocoronary revascularization [16,17], although residual coronary artery disease may be a determinant of left ventricular function exercise response after surgery and this does not necessarily imply graft occlusion [18].…”

122. Verbesserung der regionalen Myokardfunktion durch die aortocoronare Bypass-Operation ? Nichtinvasive Untersuchungen mit der First-Pass-Technik

“…Zur exakten Analyse der h~imodynamischen Effekte der Revascularisation sind Methoden, die eine regionale Bewertung entsprechend den Versorgungsgebieten der einzelnen CoronargeffiBe zulassen, besser geeignet als globale Parameter, die einen Bilanzwert der einzelnen Territorien bilden und damit weniger aussagekrfiftig sind [1,4,6,9]. Die von uns angewandte Bestimmung der regionalen Ejektionsfraktion mit der First-Pass-Radionuklidangiographie hat sich als besonders sensitive Methode erwiesen [8, 9 10, 11, 12].…”