“…Studies have shown the advanced abilities of automated artificial intelligence (AI)-based imaging analysis in Radiology, especially for two reasons: complex image analyses can be performed user-independently within second-short timeframes and were shown to perform up to 11.5% percent better than radiologists, e.g., in breast cancer prediction with an AUC of 0.889 (95% CI 0.871, 0.907; n = 25,856 patients) [ 21 , 22 , 23 , 24 ]. Similar to increasing sub-specialization in medicine, available computer-based image analysis tools are focused on specified tasks, e.g., typically “emphysema”, “pulmonary embolism”, “nodule”, “aortic dissection” or more recently, “COVID-19 pneumonia” giving a precise answer to each question in disregard of coexisting pathologies [ 25 , 26 , 27 , 28 , 29 ].…”