Radiological findings and the clinical importance of megacalycosis

Kalaitzis, Christos; Patris, Emmanuel; Deligeorgiou, Evangelia; Sountoulides, Petros; Bantis, Athanasios; Giannakopoulos, Stilianos; Touloupidis, Stavros

doi:10.2147/rru.s81519

Cited by 11 publications

(12 citation statements)

References 10 publications

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“…7 Approximately 100 cases with unilateral or bilateral megacalyces have been described in the literature to date. 8 It is primarily a disease of the renal calyces, and it is usually diagnosed because of its complica-tions, such as calculi or infections of the urinary tract. CMP can be also diagnosed prenatally.…”

Section: Discussionmentioning

confidence: 99%

Staghorn stone in megapolycalicosis in a child: Still the case for open surgery? Case report

Marte

2022

Pediatr Med Chir

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We here report a rare case of congenital megapolycalicosis in a 14-year-old girl complicated by a 24-mm staghorn stone and numerous calculi at the level of all caliceal groups that had become symptomatic in recent weeks with malaise, hematuria, and urinary tract infection. Among the various therapeutic options, we opted for open surgery. The staghorn stone was removed by pyelotomy, and washout of the caliceal cavities released numerous microcalculi of 1.5−9 mm in size that were then removed. To our knowledge, this is the first case of pediatric megacapolycalicosis complicated by staghorn stone, which presents complex problems for the diagnosis and therapy.

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Section: Discussionmentioning

confidence: 99%

Staghorn stone in megapolycalicosis in a child: Still the case for open surgery? Case report

Marte

2022

Pediatr Med Chir

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“…Megacalycosis may be unilateral or bilateral and is a nonprogressive dilatation of the calyces occasionally accompanied by lithiasis, infection, and hematuria, but with normal renal function. In most cases, the renal pelvis and ureters are not dilated, although primary megaureter can occur with megacalyces [ 14 , 15 ]. Although usually sporadic, the occurrence of familial megacalyces with autosomal inheritance has supported the possible genetic nature of the malformation [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Schinzel-Giedion Syndrome with Congenital Megacalycosis in a Turkish Patient: Report of SETBP1 Mutation and Literature Review of the Clinical Features

Bulut

İnce

Altunoğlu

et al. 2017

Case Reports in Genetics

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Schinzel-Giedion syndrome (SGS) is a rare autosomal dominant disorder that results in facial dysmorphism, multiple congenital anomalies, and an increased risk of malignancy. Recently, using exome sequencing, de novo heterozygous mutations in the SETBP1 gene have been identified in patients with SGS. Most affected individuals do not survive after childhood because of the severity of this disorder. Here, we report SETBP1 mutation confirmed by molecular analysis in a case of SGS with congenital megacalycosis.

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“…In the case of absence of such a relation, the isolated collecting system dilation (usually on one side) may prove an anatomical defect in the form of megacalycosis, which imitates pelvicalyceal system dilation, but does not entail problems with urinary outflow from the kidney and does not require any procedure to be performed. Ultrasound shows then visible multiple dilated renal calyces (over 20–25 pieces) and a correct renal pelvis ( 5 ) .…”

Section: Discussionmentioning

confidence: 99%

USG nerek – co jest istotne dla urologa?

2016

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Kidney ultrasound is one of the basic procedures in the practice of a urologist. Apart from the location and the size, description of renal morphology should contain the thickness of the anterior lip parenchyma in a transverse section and the location of possible narrowings. Uneven outline of the kidney is a sign of past inflammatory conditions. In the case of the pelvicalyceal system dilation, it is advised to specify the dimensions of the pelvis and calyces. Convex shape of the calyces proves elevated pressure within the pelvicalyceal system. Hydronephrosis is present when urinary retention has led to thinning the renal parenchyma. In each case, one should identify the reason for urinary retention in the upper urinary tract. Urinary retention on both sides requires one to exclude urinary bladder tumor, it may also be caused by a benign prostatic hyperplasia. Ultrasound examination is a sensitive method of renal stones detection, regardless of their chemical composition. Cyst description in an ultrasound image should cover its morphological features, differentiating between the so-called simple or complex cysts. In the case of a solid lesion, ultrasound makes it possible to detect parenchymal lesions usually starting with the size of 2–2.5 cm. It enables one to particularly diagnose angiomyolipomas. As regards the remaining parenchymal lesions, differentiation of the lesion nature is impossible. In some cases of angiomyolipoma, when it contains bleeding areas present and when it is deficient in adipose tissue, it resembles adenocarcinoma. It is necessary that the description includes the exact location, especially the dimensions and relation of the tumor to the renal sinus. In the case of larger lesions, respiratory motion of the kidney, the condition of the adrenal gland and the presence of enlarged lymph nodes should be controlled. Additionally, one should evaluate the renal vein and inferior vena cava in terms of a neoplastic plug presence.

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Radiological findings and the clinical importance of megacalycosis

Cited by 11 publications

References 10 publications

Staghorn stone in megapolycalicosis in a child: Still the case for open surgery? Case report

Staghorn stone in megapolycalicosis in a child: Still the case for open surgery? Case report

Schinzel-Giedion Syndrome with Congenital Megacalycosis in a Turkish Patient: Report of SETBP1 Mutation and Literature Review of the Clinical Features

USG nerek – co jest istotne dla urologa?

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