Radiological Features of Germinoma Arising From Atypical Locations-Three Case Reports-

Abstract

Three cases of intracranial germinoma arising from atypical locations occurred in 13-, 22-, and 28-yearold males. The location of the tumor was the corpus callosum (2 cases) and the temporal lobe. Computed tomography and magnetic resonance imaging showed all three tumors had a largest dimension, including the internal cyst, of over 6 cm, and the cysts were larger than 2.5 cm. Radiotherapy and chemotherapy caused all tumors to disappear. Large tumor and large cyst are features of germinoma arising from atypical locations.

Basal ganglia germinomas in children. Four clinical cases and a literature review

“…Несахарный диабет часто является первым и единственным симптомом заболевания при герми-номах супраселлярной области, причем в некоторых случаях он появляется до визуализации опухоли на МРТ [11,12]. В наших наблюдениях несахарный диабет в наблюдении 1 диагностирован за 2 года до появления гемипареза, в наблюдении 2 он развился через 8 мес после появления мышечной слабости в конечностях, в наблюдениях 3 и 4 он отсутствовал.…”

Atypical Location of Intracranial Germinoma: A Case Report

“…Other sites have rarely been described, including the corpus callosum [2], the corona radiata [3], and the frontal lobe [4]. The incidence of metastatic intracranial germinomas is not well established and varies largely among series.…”

Germinoma of the Corpus Callosum

“…They may also originate in the basal ganglia, cerebellopontine angle, lateral ventricle, cerebellum, frontal/temporal/occipital lobes, medulla, and, very rarely, in the corpus callosum. [1][2][3][4][5][6] Because of the unusual location of the lesion, multiple neuroradiologists failed to include germinoma in the differential diagnosis. …”

“…There are only three reports of intracranial germinomas originating in corpus callosum described in the literature, [6][7][8] only two of which have provided detailed descriptions. 6,8 In one paper, Utsuki et al describe two cases of intracranial germinoma involving the corpus callosum.…”

“…6,8 In one paper, Utsuki et al describe two cases of intracranial germinoma involving the corpus callosum. In both cases the tumours were large with with cystic components seen on the MRI, a common finding in suprasellar germinomas but that was not seen in our case.…”