Radiological evaluation for effect of NAC on tibia puncture fracture in dogs

Abstract

The present study used N- acetyl cysteine NAC to study its effects on tibia bone defects in dogs. This study aimed to evaluate the effective use of N- acetylcysteine (NAC) on tibia puncture fracture in dogs. The dogs were divided into three groups (5 dogs for each one): Control group (treated with autogenous cartilage only), treated group 1(treated with autogenous cartilage mixed with NAC), and treated group 2 (treated with autogenous cartilage and NAC orally). Radiological assessment fourteen days postoperatively, there is no evidence of periosteal reaction in the radiological examination in the control group. While the radiological findings revealed evidence of periosteal response at the ridges of the bone gap in treated group one and radiological results showed evidence of more periosteal interaction at the edges of the bone gap in treated group two compared with the group one and control group, and the gap appeared cloudy in color. Twenty-eight days postoperatively showed that the bone gap seemed dark in the shade of bone gap in control groups. Twenty-eight days postoperatively in treated group one, radiographs showed a narrowing in the bone gap diameter as showed by radiological examination.