“…48 Despite earlier assertions that the retained radiopaque dusts, like antimony, barium, iron, and tin, are neither toxic, allergenic, nor pathogenic, critical appraisal of this literature leaves room for doubt. [46][47][48][49][50][51] We recommend that a similar clinical approach be taken for patients with radiopaque dustinduced radiographic changes as is taken for patients with other interstitial lung diseases. If a detailed history reveals respiratory symptoms or if pulmonary physiology, including measurements of gas exchange, is abnormal, the patient should proceed to biopsy or, if reluctant, they should at least receive careful follow-up to detect any signs of clinical deterioration.…”