Radiologic-Pathologic Correlation of Intraosseous Lipomas

Propeck, Tim; Bullard, Mary Anne; Lin, John; Doi, Kei; Martel, William

doi:10.2214/ajr.175.3.1750673

Cited by 76 publications

(77 citation statements)

References 7 publications

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“…(1,6) The true prevalence in the general population may be higher, as this lesion is commonly asymptomatic and its radiographic features may lead to it being labelled as benign without further characterisation. Pathologic interpretation of this lesion in the absence of radiological correlation may sometimes be misleading, as histologically, an intraosseous lipoma can be difficult to differentiate from normal fat in yellow marrow or from osteonecrosis.…”

Section: Intraosseous Lipomamentioning

confidence: 99%

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Benign periarticular, bone and joint lipomatous lesions

Kheok¹,

Ong²

2017

smedj

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Section: Intraosseous Lipomamentioning

confidence: 99%

“…(1,6) Magnetic resonance (MR) imaging shows the lesion to be isointense to subcutaneous fat on T1-and T2-weighted images, and hypointense on fat-saturated sequences. Compared to the surrounding normal bone marrow, the lesion has mildly higher T1-weighted signal intensity.…”

Section: Intraosseous Lipomamentioning

confidence: 99%

Benign periarticular, bone and joint lipomatous lesions

Kheok¹,

Ong²

2017

smedj

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“…Diagnosis of a intraosseous lipoma with simple plain x-ray may be difficult, however the presence of intalesional calcification may aid in diagnosis. 6 MRI is an excellent method for demonstrating fatty tissue, and its primary role in the identification of intraosseous lipomas is to visualize fat within the lesions. On T1-and T2-weighted sequences the matrix content of the lesion shows similar features of those of fat tissue like bone marrow fat and subcutaneous fat.…”

Section: Discussionmentioning

confidence: 99%

Intraosseous lipoma - A rare cause of ‘cystic’ lesion of calcaneum

et al. 2016

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Intraosseous lipoma is an uncommon benign bone neoplasm with most of them detected incidentally on multimodality imaging while being evaluated for an unrelated pathology. Long and cancellous bones are commonly involved. This lesion can present a diagnostic challenge to those uninitiated in its appearence because they can be often mistaken for other benign or malignant bone lesions such as enchondroma, fibrous dysplasia, osteoblastoma, bone infarct, bone cyst and chondrosarcoma. Here we report a case of symptomatic calcaneal lipoma in a 50 year old lady who presented with heel pain. Plain X-ray suggested cystic lesion of calcaneum. MRI revealed the presence of intralesional fat and histopathological examination confirmed the diagnosis. We present this report for its rarity and the clinching MRI features of this lesion, the excellent prognosis and near negligible recurrence rates, so that misdiagnosis leading to unnecessary workup, biopsy and treatment may be avoided, especially in asymptomatic patients.

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“…On CT scans, the attenuation value of normal fatty marrow is slightly greater than that of IMLs [6]. MRI is highly sensitive for detection of IMLs, which have signal intensity similar to that of subcutaneous adipose tissue on T1 and T2 weighted images and demonstrate fat "drop-out" on fat suppressed or STIR sequences [7][8][9]. In addition, the thin capsular rim can be clearly identified on the MRI.…”

Section: Discussionmentioning

confidence: 99%

Intraosseous Lipoma with Subsequent Esophageal Carcinoma Metastasis

Singh¹,

John²,

Priya³

et al. 2012

OJMI

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Background: This case report describes a well documented proximal femoral metadiaphysis intraosseous lipoma which later developed metastasis from a new esophageal cancer. Metastatic disease to benign conditions is a rare finding. To the best of our knowledge, this is the first reported case of metastatic disease to an intraosseous lipoma. Case Description: The metastatic deposit was initially detected by plain-film radiography, performed to evaluate new onset right hip pain, as possible new cortical breakthrough with irregularity in the site of previously known proximal right femur intraosseous lipoma. Concurrent follow-up PET/CT study showed a new hypermetabolic focus within the known intraosseous lipoma indicating a new metastasis that was confirmed with an MRI as a new enhancing mass within the preexisting intraosseous lipoma. Subsequently, an MRI-guided biopsy and eventually surgical excision was performed providing the histological samples for radiologic-pathologic correlation. Purpose and Clinical Relevance: Clinicians need to be aware that unusual, complex patterns within benign lesions may be a reflection of unexpected conditions, such as insufficiency injury, malignant transformation and secondary metastatic disease, as exemplified by our case report.

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Radiologic-Pathologic Correlation of Intraosseous Lipomas

Cited by 76 publications

References 7 publications

Benign periarticular, bone and joint lipomatous lesions

Benign periarticular, bone and joint lipomatous lesions

Intraosseous lipoma - A rare cause of ‘cystic’ lesion of calcaneum

Intraosseous Lipoma with Subsequent Esophageal Carcinoma Metastasis

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