Radioimmunoguided surgery system improves survival for patients with recurrent colorectal cancer

Radioimmunoguided surgery in colorectal cancer: A 6-year experience with four different technical solutions

“…Although we attempted several methodological options within our 6-year experience, no definitive results could be obtained. We believe that widespread use of RIGS in colorectal cancer surgery should be supported by further technical improvements and by the evaluation of newer MAbs such as CC49 and CC83 [9,10]. Research is needed to further develop techniques that may increase the antigen immunological expression at the tumor site through the use of biological response modifiers [11,12] or the avidin-biotin system to increase RIGS utility.…”

Intraoperative localization of gut endocrine tumors with radiolabeled somatostatin analogs and a gamma-detecting probe

“…The radioimmunoguided surgery method has been used in recent years for the identification of tumors otherwise not detected by visual inspection or palpation in patients with colo-rectal cancer [9,10,24].…”

Role of tumor-associated antigen expression in radioimmunoguided surgery for colorectal and breast cancer

“…Efforts have been made to use MAbs with new characteristics including rapid uptake by tumor tissues, high affinity for TAA, and, possibly, rapid clearance from normal tissues [7][8][9].…”