Radiohalogens for Molecular Imaging (Fluorine and Iodine)

Accurate Formulae for the Cross-Section Data for the Radio-Halogen I-123 from Cyclotron Production

“…Additionally, radioisotopes of bromine are not typically employed in clinical settings. Among the halogens, iodine is the most powerful agent for reducing [1] [2].…”

“…It decays by electron capture mode with 100% branching, with two main gamma rays 0.028 and 0.160 MeV. There are two main ways to produce a 123I: The first is the direct method as shown in Equation (1), while the second is through the production of 123Xe, which in turn is left to decompose to 123I shown in Equation (2). The second method has the advantage of easily separating the xenon from the original target material and allowing it to decay separately, giving I-123 very little contamination from other radioactive isotopes of iodine [4]…”