Radioguided Sentinel Lymph Node Mapping and Biopsy in Cutaneous Melanoma

Nieweg, Omgo E.; Uren, Roger F.; Thompson, John F.

doi:10.1007/978-3-319-26051-8_10

Cited by 1 publication

(1 citation statement)

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“…General anaesthesia is usual. However, in a recent audit at the Melanoma Institute Australia the postoperative complication rate for an SN biopsy was found to be only 2%, and the complications that did occur were generally minor and tended to resolve quickly and completely …”

Section: Other Benefits and Risksmentioning

confidence: 99%

Role of sentinel lymph node biopsy as a staging procedure in patients with melanoma: A critical appraisal

2017

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Worldwide, sentinel node (SN) biopsy for accurate staging is now part of the standard work-up of patients with melanomas ≥1.0 mm Breslow thickness, as it is for staging patients with breast cancer. Nuclear medicine imaging and surgical techniques have evolved to such a degree that a SN can be identified and removed in virtually every patient. Nevertheless, some opposition to a routine SN biopsy remains, perhaps due to a failure to appreciate the serious implications of incomplete or inaccurate staging. Guided by a critical appraisal of the available evidence, this review elucidates the definition of an SN, discusses the sensitivity and specificity of the information it provides, emphasises that it is a minor staging procedure that can lead to improved survival when followed by appropriate therapy, and explains the necessarily unconventional and complex design of the only randomised trial that addresses this subject. It also describes other benefits and risks of an SN biopsy and outlines its role in current melanoma management.

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Section: Other Benefits and Risksmentioning

confidence: 99%