Radiographic methods for evaluating osteoporotic vertebral fractures

Grados, Franck; Fechtenbaum, J.; Flipon, Elisabeth; Kolta, Sami; Roux, Christian; Fardellone, Patrice

doi:10.1016/j.jbspin.2008.07.017

Cited by 103 publications

(71 citation statements)

References 58 publications

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“…Further analyses will be necessary to determine whether similar reproducibility is seen when applying the GSQ method to incident fracture analysis in children. In adults the reproducibility is similar for both prevalent and incident fractures, but this remains to be seen in pediatric imaging [1,2,39]. As a final point, our study specifically involved children with ALL.…”

Section: Discussionmentioning

confidence: 95%

Observer agreement in pediatric semiquantitative vertebral fracture diagnosis

et al. 2013

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Section: Discussionmentioning

confidence: 95%

Observer agreement in pediatric semiquantitative vertebral fracture diagnosis

et al. 2013

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“…Visual assessment of vertebral fracture on plain radiographs is notoriously subjective [3] so semi-quantitative and quantitative schemes have been developed to measure vertebral body deformity as a more reproducible indicator of fracture [1,2,4,5].…”

Section: Introductionmentioning

confidence: 99%

Vertebral deformity arising from an accelerated “creep” mechanism

et al. 2012

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Introduction Vertebral deformities often occur in patients who recall no trauma, and display no evident fracture on radiographs. We hypothesise that vertebral deformity can occur by a gradual creep mechanism which is accelerated following minor damage. ''Creep'' is continuous deformation under constant load. Materials and methods Forty-five thoracolumbar spine motion segments were tested from cadavers aged 42-92 years. Vertebral body areal BMD was measured using DXA. Specimens were compressed at 1 kN for 30 min, while creep in each vertebral body was measured using an optical MacReflex system. After 30 min recovery, each specimen was subjected to a controlled overload event which caused minor damage to one of its vertebrae. The creep test was then repeated. Results Vertebral body creep was measurable in specimens with BMD \0.5 g/cm 2 . Creep was greater anteriorly than posteriorly (p \ 0.001), so that vertebrae gradually developed a wedge deformity. Compressive overload reduced specimen height by 2.24 mm (STD 0.77 mm), and increased vertebral body creep by 800 % (anteriorly), 1,000 % (centrally) and 600 % (posteriorly). In 34 vertebrae with complete before-and-after data, anterior wedging occurring during the 1st creep test averaged 0.07°(STD 0.17°), and in the 2nd test (after minor damage) it averaged 0.79°(STD 1.03°). The increase was highly significant (P \ 0.001). Vertebral body wedging during the 2nd creep test was proportional to the severity of damage, as quantified by specimen height loss during the overload event (r 2 = 0.51, p \ 0.001, n = 34). Conclusions Minor damage to an old vertebral body, even if it is barely discernible on radiographs, can accelerate creep to such an extent that it makes a substantial contribution to vertebral deformity.

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“…In the same way, several methods have been found to semi-quantitatively or quantitatively detect VFs. The visual semi-quantitative assessment on conventional spine radiographs [10] remains the most validated and used method in clinical practice; however, some authors support a combined approach of visual semi-quantitative and quantitative morphometric methods to overcome limits of single methods side by side [11,12].…”

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confidence: 99%

Reliability and accuracy of scout CT in the detection of vertebral fractures

Bazzocchi

Fuzzi

Garzillo

et al. 2013

BJR

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Objective: The aim of the present study was to evaluate the reliability of scout CT (sCT) lateral radiograph, in terms of diagnostic accuracy and intra-and interobserver agreement in the detection of vertebral fractures (VFs). Methods: 300 CT examinations of the thoracic and/or lumbar spine were collected and independently analysed by 3 musculoskeletal radiologists in 2 different sessions. A semi-quantitative approach was used for VF assessment on sCT, and morphometric analysis was performed when a VF was suspected. Results of multiplanar sagittal CT reconstructions interpreted by the most expert radiologist were considered as gold standard. Arthrosis was also scored. Only vertebral bodies assessable by both sCT and gold standard were considered for the analysis. Area under the receiver operating characteristic curve (AUROC), Cohen's kappa statistic and linear-by-linear association were used for statistical analysis.

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Radiographic methods for evaluating osteoporotic vertebral fractures

Cited by 103 publications

References 58 publications

Observer agreement in pediatric semiquantitative vertebral fracture diagnosis

Observer agreement in pediatric semiquantitative vertebral fracture diagnosis

Vertebral deformity arising from an accelerated “creep” mechanism

Reliability and accuracy of scout CT in the detection of vertebral fractures

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