Here, we investigate early Permian adakites from Inner Mongolia, North China. The adakites are found along the Hegenshan suture zone, were emplaced into the late Carboniferous Meilaotewula suprasubduction zone (SSZ) ophiolite and consist mainly of fine‐ to medium‐grained granodiorites. U–Pb zircon dating reveals that the Meilaotewula adakites crystallized at 292 Ma. The adakites belong to the low‐K tholeiitic and medium‐K calc‐alkaline series. They are characterized by high SiO2 (65.20–70.05 wt.%), Al2O3 (16.46–19.27 wt.%), and Sr (343–666 ppm); low MgO (1.26–1.95 wt.%), Yb (0.65–1.16 ppm), and Y (8.08–10.6 ppm) contents; and Na2O/K2O ratios (3.26–10.73). They are relatively enriched in large‐ion lithophile elements, such as K, Rb, and Sr, and depleted in high‐field‐strength elements, such as Nb, Ta, Zr, Ti, and P, and have low total rare‐earth element (REE) contents (27.73–49.63 ppm), with distinct REE fractionation (chondrite‐normalized La/Yb of 3.05–8.88) and no pronounced negative Eu anomalies. The rocks have relatively low initial 87Sr/86Sr values (0.70285–0.70326), high εNd(t) values (+8.8 to +10.8), and relatively high zircon εHf(t) values (11.9 to 15.9), indicating that the magma was derived from young juvenile oceanic crust derived from depleted mantle, similar to adakitic rocks formed by partial melting of subducted oceanic crust. The relatively high Mg# of the adakites indicates that the melts interacted with mantle peridotite during ascent. The adakites, together with Meilaotewula ophiolite (308 Ma), may have formed during the early stages of intra‐oceanic subduction, demonstrating that subduction initiation in the southeastern Palaeo‐Asian Ocean occurred during the late Carboniferous to early Permian.