Radiofrequency-Treated Recurrence of Urothelial Carcinoma of the Upper Urinary Tract After Nephroureterectomy

Abstract

Local recurrence after radical nephroureterectomy (RNU) owing to urothelial carcinoma of the upper urinary tract is rare. The usual treatment is systemic chemotherapy followed by optional resection of the mass. We introduce the case of a 73-year-old male patient with multiple comorbidities in whom retroperitoneal carcinoma recurrence of 31 mm was diagnosed via positron emission tomography-computed tomography scan with 18-fluorodeoxyglucose about 5 years after he had undergone RNU owing to urothelial carcinoma of the upper urinary tract. The patient was treated with computed tomography-guided percutaneous radiofrequency ablation. Later scans with contrast controls showed lack of contrast uptake and a decrease of the lesion's size. Twenty-four months after the procedure, the patient is free of the disease. To date, this is the first case of recurrence of urothelial carcinoma that was treated with percutaneous radiofrequency ablation, thus establishing an alternative to chemotherapy in patients with substantial comorbidities.

The efficacy and safety of microwave ablation in patients with retroperitoneal metastases

“…c W: Watt. summarised a total of 18 studies, which included 398 patients with 491 retroperitoneal tumours that were treated with thermal ablation, and showed that the ORR ranged from 74.5% to 100.0% [1][2][3][4][5][6][7][8][9][10][37][38][39][40][41][42].…”

A Spectrum of Entities That May Mimic Abdominopelvic Abscesses Requiring Image-guided Drainage

“…Upper tract urothelial neoplasms account for approximately 10% of renal neoplasms and 5% of urothelial neoplasms (27). Patients with upper tract urothelial neoplasms are typically treated surgically, including nephroureterectomy and removal of a cuff of urinary bladder (28).…”