2013
DOI: 10.1186/1477-7819-11-190
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Radiofrequency ablation versus hepatic resection for the treatment of early-stage hepatocellular carcinoma meeting Milan criteria: a systematic review and meta-analysis

Abstract: Current options for the treatment of the early-stage HCC conforming to the Milan criteria consist of liver transplantation, hepatic resection (HR), transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) .Whether HR or RFA is the better treatment for early HCC has long been debated. The aim of our paper is to compare the therapeutic effects of radiofrequency ablation (RFA) and hepatic resection (HR) in the treatment of early-stage hepatocellular carcinoma (HCC). Controlled trials eval… Show more

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Cited by 66 publications
(51 citation statements)
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“…These results corresponded with those of a previous meta-analysis in which VASCULAR AND INTERVENTIONAL RADIOLOGY: Radiofrequency Ablation versus Resection for Small Hepatocellular Carcinoma Kang et al RF ablation and hepatic resection were compared (40). Our study had several limitations.…”
Section: Vascular and Interventional Radiology: Radiofrequency Ablatisupporting
confidence: 88%
“…These results corresponded with those of a previous meta-analysis in which VASCULAR AND INTERVENTIONAL RADIOLOGY: Radiofrequency Ablation versus Resection for Small Hepatocellular Carcinoma Kang et al RF ablation and hepatic resection were compared (40). Our study had several limitations.…”
Section: Vascular and Interventional Radiology: Radiofrequency Ablatisupporting
confidence: 88%
“…An idea simultaneously developed in four labs across the world 12,13,14,15 it was the reverse of stereotaxy; instead of finding a location on an image and moving to it, the present surgical position and trajectory were digitized and the location displayed on the images. One remarkable aspect to this development was that it arose from surgeon/engineer teams.…”
Section: Examplesmentioning
confidence: 99%
“…Surgical resection is associated with greater OS and DFS rates than RFA, according to the results of a 2013 systematic review and meta-analysis covering two RCTs and 10 non-RCTs; however, ablation is associated with fewer post-treatment complications and shorter hospital stays [58]. Conversely, there are data from other RCTs showing comparable long-term survival outcomes with resection and RFA [59,60].…”
Section: Consensus Recommendationsmentioning
confidence: 99%