Radiofrequency Ablation After Breast Lumpectomy Added to Extend Intraoperative Margins in the Treatment of Breast Cancer (ABLATE): A Single-institution Experience

Mackey, Aimee; Feldman, Sheldon; Vaz, Amiya; Durrant, Lara M.; Seaton, Christopher; Klimberg, V. Suzanne

doi:10.1245/s10434-012-2293-7

Cited by 5 publications

(2 citation statements)

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“…Currently, a range of percutan eous techniques for the treatment of nonpalpable breast cancers are in development. These techniques have been used to ablate cavity margins after standard surgical excision, [96][97][98][99] as well as to ablate the primary cancer itself. [100][101][102] Owing to the percutaneous instrumental manipulation involved, these techniques can have similar complications to standard surgery, including scarring, skin burns, haematomas, and infection.…”

Section: Minimally Invasive Percutaneous Surgerymentioning

confidence: 99%

Surgical treatment of nonpalpable primary invasive and in situ breast cancer

et al. 2015

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Breast cancer is the most-common cancer among women worldwide, and over one-third of all cases diagnosed annually are nonpalpable at diagnosis. The increasingly widespread implementation of breast-screening programmes, combined with the use of advanced imaging modalities, such as magnetic resonance imaging (MRI), will further increase the numbers of patients diagnosed with this disease. The current standard management for nonpalpable breast cancer is localized surgical excision combined with axillary staging, using sentinel-lymph-node biopsy in the clinically and radiologically normal axilla. Wire-guided localization (WGL) during mammography is a method that was developed over 40 years ago to enable lesion localization preoperatively; this technique became the standard of care in the absence of a better alternative. Over the past 20 years, however, other technologies have been developed as alternatives to WGL in order to overcome the technical and outcome-related limitations of this technique. This Review discusses the techniques available for the surgical management of nonpalpable breast cancer; we describe their advantages and disadvantages, and highlight future directions for the development of new technologies.

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Section: Minimally Invasive Percutaneous Surgerymentioning

confidence: 99%

Surgical treatment of nonpalpable primary invasive and in situ breast cancer

et al. 2015

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“…However, the combined treatment did not show better tumor suppressive effect than RFA alone in mice with large tumors at the time of treatment. Several reports using RFA for human breast cancer treatment usually select an average tumor volume from 0.775 cm to 2.08 cm or at early stage (8,(26)(27)(28)(29)(30)(31). It is reasonable that heat transduction should be more efficient in small tumors.…”

Section: Discussionmentioning

confidence: 99%