Radiocontrolled Movement of a Robot Endoscope in the Human Gastrointestinal Tract

Swain, Paul; Mills, Thomas M.; Kelleher, Brian; Schmitz, Loren; Mosse, Sandy; Burke, P.S.; Ikeda, Keiichi; Fritscher-Ravens, Annette

doi:10.1016/s0016-5107(05)00660-7

Cited by 3 publications

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“…This radio-controlled electrostimulation capsule (RESC) was further tested in the GI tract of a healthy volunteer (2005). 32 Although showing great promise, no commercial product has been released based on this technology. A similar electrically stimulated capsular propulsion system was reported by Woo et al 33 from South Korea in 2011 [ Fig.…”

Section: A1 Active Locomotionmentioning

confidence: 99%

“…Their capsule incorporates a pair of peripheral electrodes for circular stimulation of the intestinal muscles; 12–15 electrostimulations per second was reported to cause localized muscular contraction that propels the device up to 6 mm s −1 and 4.5 mm s −1 in either direction of a porcine esophagus and small intestine, respectively. This radio‐controlled electrostimulation capsule (RESC) was further tested in the GI tract of a healthy volunteer (2005) . Although showing great promise, no commercial product has been released based on this technology.…”

Section: State Of the Art In Research And Developmentmentioning

confidence: 99%

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Magnetically guided capsule endoscopy

et al. 2017

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Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which was previously inaccessible to classical flexible endoscopy. As a diagnostic tool, it allows to localize the sources of bleedings in the middle part of the gastrointestinal tract and to identify diseases, such as inflammatory bowel disease (Crohn's disease), polyposis syndrome, and tumors. The screening and diagnostic efficacy of the WCE, especially in the stomach region, is hampered by a variety of technical challenges like the lack of active capsular position and orientation control. Therapeutic functionality is absent in most commercial capsules, due to constraints in capsular volume and energy storage. The possibility of using body-exogenous magnetic fields to guide, orient, power, and operate the capsule and its mechanisms has led to increasing research in Magnetically Guided Capsule Endoscopy (MGCE). This work shortly reviews the history and state-of-art in WCE technology. It highlights the magnetic technologies for advancing diagnostic and therapeutic functionalities of WCE. Not restricting itself to the GI tract, the review further investigates the technological developments in magnetically guided microrobots that can navigate through the various air-and fluid-filled lumina and cavities in the body for minimally invasive medicine.

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Section: A1 Active Locomotionmentioning

confidence: 99%

Section: State Of the Art In Research And Developmentmentioning

confidence: 99%

Magnetically guided capsule endoscopy

et al. 2017

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“…All those who carry out CE hope that it will become possible in the near future to have radio control of the video capsule and take tis− sue samples. An autonomous radio−controlled robotic capsular endoscope (RESC) measuring 11 33 mm, with forward and re− verse movement functions, has been tested in the porcine and hu− man gastrointestinal tract [19]. The RESC was constructed to pro− pel and control the direction of movement of a wireless capsule endoscope, to which it was attached by a short cable, by means of circular muscular contraction in the gut.…”

Section: Innovationsmentioning

confidence: 99%

Capsule Endoscopy

Pennazio¹

2005

Endoscopy

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IntroductionThis year's Digestive Disease Week saw the presentation of more than 80 studies focusing on capsule endoscopy (CE); this review discusses in detail the 20 most significant of these. Alongside various reports concerning technical aspects of the procedure, possible new applications have been studied, including in celiac disease. Obscure bleeding is now a consolidated indication to CE; however, prospective data on the impact of CE on clinical out− comes are still scarce. Opinions diverge on the effective role of CE in Crohn's disease, and further research is needed to define this role. Research is also underway to develop capsules with propulsive and therapeutic capabilities. The strong interest in small−bowel endoscopy is also shown by the numerous studies concerning double−balloon enteroscopy, a complementary pro− cedure to CE ( Figure 1). Technical Factors, Assessment, and Other AspectsThe time spent by the physician in evaluating the images appears to be the most costly part of CE. The increasing number of pre− scriptions of CE makes it imperative to evaluate whether other health professionals may be able to replace the doctor in the ini− tial reading of the film. In one study, 20 consecutive CE exams were reviewed by one CE−experienced gastroenterologist and by one endoscopy nurse and one resident previously trained in CE [1]. The gastroenterologist's sensitivity for "overall lesions" was lower and the specificity higher compared with both nurse and resident (with sensitivities of 79 %, 86 %, and 80 %, respectively, and specificities of 99 %, 43 %, and 57 %). Interobserver agreement for "overall lesions" was discrete to moderate (kappa 0.62, 0.30, and 0.33 for gastroenterologist, nurse, and resident, respectively) and excellent for "significant lesions" (kappa = 1 for all readers). In another prospective study, 50 CE videos were preread by a specially−trained gastroenterology nurse, who thumbnailed ab− normalities detected for interpretation by the gastroenterologist [2]. There was complete agreement between the nurse and the gastroenterologist for all 12 cases interpreted as normal by the gastroenterologist. In the remaining 38 cases, the nurse created 130 thumbnail selections and the physician 99. Complete inter− observer agreement was achieved for 93 of the 96 lesions cate− gorized as "significant" by the physician (96.9 %). This approach was reported to save $ 324 per CE examination. BleedingIt is still not entirely clear whether CE or push enteroscopy (PE) is the most efficient strategy in terms of diagnosis and therapeutic impact in patients with obscure gastrointestinal bleeding (OGIB). An interesting prospective randomized study [3] compared a strategy based on one or the other examination in 78 patients. The alternative examination was only performed when no lesion was evidenced in the first one, or in case of clinical necessity dur− ing the 1−year follow−up period. The percentage of patients hav− ing to undergo the alternative examination was 74 % for CE and 77 % for PE. If the 100 % negat...

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History and Future

Swain¹

2008

Capsule Endoscopy

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Radiocontrolled Movement of a Robot Endoscope in the Human Gastrointestinal Tract

Cited by 3 publications

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Magnetically guided capsule endoscopy

Magnetically guided capsule endoscopy

Capsule Endoscopy

History and Future

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