Radiobiological Effects of Photon Radiosurgery on Choroid Plexus Cells in Vitro

Hq, Niu; Eckhardt, Klaus; Cb, Ostertag

doi:10.1055/s-2003-39343

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Device Description and Dosimetry1

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2009

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“…The isotropic radiation shows a dose decline rate of approximately 1/r 3 and has a similar dosimetry compared with Linac radiosurgery and proton beam in small spherical intracranial tumors (11,12). The radiobiological effects of PRS irradiation, such as an early cell death through a nonapoptotic pathway, were demonstrated at several rodent and human cell lines (13)(14)(15). Focal radionecrotic lesions were demonstrated in animal models, and hyperthermia as a possible tumoricidal factor has been excluded (16).…”

Section: Device Description and Dosimetrymentioning

confidence: 99%