Radioactive Seed Localization for Nonpalpable Breast Lesions in a Community Hospital Setting

Wheeler, James; Harrod, Karlyn K.; Liu, Fang; Garber, Elizabeth; Grove-Narayan, Lisa; Moore, Adam

doi:10.5539/cco.v5n1p25

Cited by 1 publication

(2 citation statements)

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“…The analysis of our first 48 RSL patients (Wheeler et al, 2016) indicated the specimen weight was significantly larger for the RSL patients (average of 63 g) compared to the WL patients (average of 33 g; p=0.02). Since a larger specimen size could cause an inferior cosmetic result, it was encouraging that with the added experience accumulated with the second year of the RSL program, the difference in the specimen size no longer was significant, with a geometric mean of 32.78 g for the RSL patients compared to 30.26 for the WL patients, p-value 0.553.…”

Section: Discussionmentioning

confidence: 99%

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Initial Community Hospital Performance of Radioactive Seed Localization for Breast Cancer Patients

Wheeler¹,

Liu²

2017

CCO

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Purpose: To compare the positive margin rates for women with nonpalpable breast tumors who underwent breast conserving surgery with wire localization versus those with radioactive seed localization in a small community hospital and to compare the size of the corresponding breast specimens. Introduction:Wire localization (WL) has been the standard technique to assist in the removal of nonpalpable breast tumors for the past three decades for patients undergoing breast conserving surgery. Radioactive seed localization (RSL) is an alternative technique that provides advantages of patient comfort and scheduling convenience. There are numerous studies from large academic centers, but little information on how successfully this technique can be implemented in community hospitals. Results: Three of the 35 WL patients (8.5%) had a positive margin compared to 14 of the 110 RSL patients (12.7%), but this difference was not statistically significant (p-value 0.763). The breast specimen weight had a geometric mean of 30.26 g for the WL patients and 32.78 g for the RSL patients, a difference of 8.3%, which was not statistically significant. Positive margin rates did not depend on the surgeon or the radiologist placing the I-125 localization seed. Conclusion:The RSL technique can be implemented in community hospitals with the expectation of having the same positive margin rates as reported from academic centers.

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Section: Discussionmentioning

confidence: 99%

“…We reported on our initial 2014 experience comparing 48 RSL patients and 36 WL patients from our community hospital (Wheeler et al, 2016). Our initial positive margin rate was not statistically different between the WL (8.3%) and RSL (10.4%) patients, but the specimen weight was larger for the RSL patients (63 g) than for the WL patients (33 g; p = 0.02).…”

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confidence: 92%

Initial Community Hospital Performance of Radioactive Seed Localization for Breast Cancer Patients

Wheeler¹,

Liu²

2017

CCO

Self Cite

View full text Add to dashboard Cite

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Radioactive Seed Localization for Nonpalpable Breast Lesions in a Community Hospital Setting

Abstract: Purpose: To compare the positive margin rates for women with nonpalpable breast tumors whom had wire localization compared to radioactive seed localization in a small community hospital.

Cited by 1 publication

References 16 publications

Initial Community Hospital Performance of Radioactive Seed Localization for Breast Cancer Patients

Initial Community Hospital Performance of Radioactive Seed Localization for Breast Cancer Patients

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