Optical images and spectra, both ground based and taken by Hubble Space Telescope (HST ), of the young, luminous O-rich supernova remnant in the irregular galaxy NGC 4449 are presented. HST images of the remnant and its local region were obtained with the ACS/ WFC using filters F435W, F555W, F814W (B, V, and I, respectively),, and F550M (line-free continuum). These images show an unresolved remnant ( FWHM < 0:05 00 ) located within a rich cluster of OB stars which itself is enclosed by a nearly complete interstellar shell seen best in H + [N ii] emission approximately 8 00 ; 6 00 (150 pc ; 110 pc) in size. The remnant and its associated OB cluster are isolated from two large nearby H ii regions. The ACS [O iii] image shows the remnant may be partially surrounded by a clumpy ring of emission approximately 1 00 ($20 pc) in diameter. Recent ground-based spectra of the remnant reveal (1) the emergence of broad, blueshifted emission lines of [S ii] kk6716, 6731, [Ar iii] k7136, and [Ca ii] kk7291, 7324 which were not observed in spectra taken in 1978Y1980; (2) faint emission at 6540Y6605 8 centered about H and [ N ii] kk6548, 6583 with an expansion velocity of 500 AE 100 km s À1 ; and (3) excess emission around 4600Y4700 8 suggestive of a Wolf-Rayet population in the remnant's star cluster. We use these new data to re-interpret the origin of the remnant's prolonged and bright luminosity and propose that the remnant is strongly interacting with dense, circumstellar wind loss material from a k20 M progenitor star.