Radical Thiocyano(Selenocyano)trifluoromethylations of Alkenes on Water
Chi Gao,
Yang Liu,
Hong‐Ye Zhu
et al.
Abstract:Trifluoromethylation‐based difunctionalization of alkenes provides a step‐economical route to CF3‐containing polyfunctionalized organics. New and scalable process is highly desired in this field. Here, we report a simple and environmentally benign method for olefinic thiocyanotrifluoromethylation. By the use of PhICF3Cl as unique CF3 agent and NaSCN as the SCN source, the difunctionalization of alkenes selectively occurs on water at ambient condition. Mechanism studies suggest a radical process in which SCN an… Show more
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