Radical cystectomy complications and perioperative mortality

Hampson, Alexander; Vincent, Amy L.; Vasdev, Nikhil

doi:10.1111/bju.14718

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…The surgical techniques and resection sequences utilized in TLRC and open RC are comparable, involving the removal of the bladder, uterus, fallopian tubes, ovaries, and anterior vagina [6] . RC is considered an incredibly complex operation with frequent complications and non-negligible high mortality [20][21][22] . Additionally, studies have shown that females who undergo RC tend to experience longer operation times and higher rates of postoperative complications compared to males [23,24] .…”

Section: Discussionmentioning

confidence: 99%

The Feasibility of Modified Laparoscopic Female Radical Cystectomy: A Procedural Guide and Comparison with Traditional Technique

chen,

Jiang,

Sun

et al. 2024

Preprint

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Females are generally less likely to develop carcinoma of the urinary bladder compared with melas. Despite radical cystectomy (RC) being an effective surgical technique, its usage in women is limited due to the decreased incidence and potential postoperative complications. We sought to evaluate the safety and feasibility of a novel modified laparoscopic radical cystectomy (MLRC) for female patients with bladder cancer and introduce the modified procedural stepwise. The retrospective cohort study spanned from January 1, 2018, to September 30, 2023, and included 45 female patients who underwent RC. Perioperative data comparison between the MLRC group (25 patients) and the traditional laparoscopic radical cystectomy (TLRC) group (20 patients) was conducted, with differences being deemed significant at P < 0.05. All operations were performed successfully without conversion to open surgery. The MLRC group exhibited less %sCre change (P < 0.001), less estimated blood loss (EBL) (P < 0.001), shorter operative time (P < 0.001), shorter pelvic lymph node dissection (PLND) time (P < 0.001), shorter first postoperative defecation (FPD) time (P < 0.001), and fewer complications (P < 0.05). However, the postoperative hospital stay, urinary reconstruction, overall survival, local recurrence or distant metastasis, and American Society of Anaesthesiology (ASA) score showed no statistical difference. Patients were followed up for 3 to 65 months, with a median of 27 months.MLRC is a safe and feasible procedure that could improve perioperative outcomes compared to traditional procedures.

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Section: Discussionmentioning

confidence: 99%

The Feasibility of Modified Laparoscopic Female Radical Cystectomy: A Procedural Guide and Comparison with Traditional Technique

chen,

Jiang,

Sun

et al. 2024

Preprint

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Fibrinogen prophylaxis for reducing perioperative bleeding in patients undergoing radical cystectomy: A double-blind placebo-controlled randomized trial

Fathi

Lashay

Massoudi

et al. 2021

Journal of Clinical Anesthesia

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Тримодальна Органозберігаюча Терапія В Сучасному Алгоритмі Лікування Первинного Низькодиференційованого М’язово-Інвазивного Раку Сечового Міхура

Yakovlev¹

2019

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РефератМета. Визначити сучасне місце тримодальної органозберігаючої терапії (ТМТ) в лікуванні первинного низькодиференційованого (G3) раку сечового міхура (РСМ). Матеріали і методи. Проаналізовані ретроспективно дані історій хвороб 346 пацієнтів з первинним G3 РСМ, оперованих за 2004 -2017 рр., а саме клінічна стадія РСМ; методи лікування: хірургічний (радикальна цистектомія/резекція), дистанційна променева терапія (ДПТ), поліхіміотерапія (ПХТ); виживаність. З причини тяжкої коморбідності 13 хворим, крім біопсії сечового міхура, подальшого хірургічного лікування не проводили. Цих хворих з аналізу ми виключили. Результати. Органозберігаюча операція виконана 224 (67%) хворим. Загальна смертність становила 63%. Післяопераційну терапію (ДПТ або ПХТ) отримали 54 (16,2%) хворих, з них 44 (81,5%) -ДПТ, 10 (18,5%) -ПХТ. Жодному пацієнту не проводили в комбінації ПХТ та ДПТ. Загальна смертність хворих, що отримали ДПТ або ПХТ, становила 80%, середня тривалість дожиття -17 та 8 міс відповідно. Висновки. Органозберігаюча хірургічна тактика в сучасному лікуванні первинного G3 РСМ займає вагоме місце: 67% усіх хворих були оперовані в обсязі резекції. ТМТ на даний час не застосовують в лікуванні G3 РСМ. Післяопераційна ПХТ або ДПТ проведена 16,2% хворих в монорежимі здебільшого з паліативною метою, що не сприяло тривалій виживаності (смертність становила 80%). Ключові слова: рак сечового міхура; м'язово-інвазивний рак; тримодальна терапія; резекція; виживаність. AbstractObjective. To determine a modern position of a three-mode organ-preserving therapy (ТHМТH) in treatment of primary lowdifferentiated (G3) cancer of thebladder (BC). Маterials and methods. Retrospective data from medical cards were analyzed in 346 patients, suffering primary G3 cancer of the bladder, who were operated in 2004 -2017 yrs, Among them there were the bladder cancer clinical stage, procedures of treatment -surgical (radical cystectomy/resection), distant radiation therapy (DRTH), polychemotherapy (PCHTH), and survival of the patients. In 13 patients further surgical treatment was not performed, their treatment was restricted by the bladder biopsy because of severe comorbidity presented. These patients were excluded from the analysis. Results. Оrgan-preserving operation was conducted in 224 (67%) patients. Total mortality have constituted 63%. Postoperative therapy (DRTH or PCHTH) have obtained 54 (16.2%) patients, of them 44 (81.5%) -DRTH, 10 (18.5%) -PCHTH. Combination of PCHTH and DRTH was not used. General mortality in the patients, who obtained DRTH or PCHTH, have constituted 80%, average duration of survival -17 and 8 mo, accordingly. Conclusion. Оrgan-preserving surgical tactics in modern treatment of primary G3 cancer of the bladder occupies prominent position: 67% of all the patients were operated, using resection. Postoperative PCHTH or DRTH was conducted in 16.2% patients in monoregime mainly with palliative objective, what did not promoted a durable survival (mortality have constituted 80%). Кeywords: the bladder cancer; musculo-invasive ca...

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Radical cystectomy complications and perioperative mortality

Cited by 3 publications

References 6 publications

The Feasibility of Modified Laparoscopic Female Radical Cystectomy: A Procedural Guide and Comparison with Traditional Technique

The Feasibility of Modified Laparoscopic Female Radical Cystectomy: A Procedural Guide and Comparison with Traditional Technique

Fibrinogen prophylaxis for reducing perioperative bleeding in patients undergoing radical cystectomy: A double-blind placebo-controlled randomized trial

Тримодальна Органозберігаюча Терапія В Сучасному Алгоритмі Лікування Первинного Низькодиференційованого М’язово-Інвазивного Раку Сечового Міхура

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