Radical Cation [2+2] Cycloadditions Enabled by Surface-Assisted Pseudo-Intramolecular Electron Transfers

Abstract

Both intermolecular and intramolecular electron transfers can be the key in the determination of synthetic outcomes of photochemical and electrochemical reactions. Herein, we report dispersed TiO2 nanoparticles in combination with methoxybenzene to be unique heterogeneous photocatalysts for facilitating the formation of novel cyclobutanes. Although the mechanistic details are as yet unclear, the results described herein imply that methoxybenzene is adsorbed onto the TiO2 surface, coming in close proximity to the forming cyclobutane radical cation, to realize a pseudo-intramolecular electron transfer between the species.

Electrochemical Organic Synthesis

“…23 Finally, Okada and his colleagues have reported their findings on radical cation [2+2] cycloadditions, made possible through surface-assisted pseudo-intramolecular electron transfers. 24 As the guest editor, I have been deeply impressed by the quality, creativity, and enthusiasm of the researchers who have contributed to this special issue. We hope that this collection of articles will serve as a valuable resource for both newcomers and seasoned researchers in the field of electrochemical organic synthesis.…”

“…23 Finally, Okada and his colleagues have reported their findings on radical cation [2+2] cycloadditions, made possible through surface-assisted pseudo-intramolecular electron transfers. 24…”