Radical cascade cyclization of 1,n-enynes under photo/electrochemical conditions

Abstract

During the past decade, photo- and electrochemical reactions proceeding via single-electron-transfer (SET) triggered radical pathways have emerged as an indispensable strategy for the efficient formation of chemical bonds. Especially, radical...

Metal-free radical bicyclization/chloroalkylarylation of 1,6-enynes with chloroalkanes

“…9 Very recently, the groups of Studer/Xuan, and Zhang separately summarized a wide range of efficient cyclization reactions of 1, n -enynes reported by numerous researchers, which result in various heterocycles. 10 Meanwhile, Li et al reported a radical bicyclization of 1,7-enynes with tert -butyl nitrite to access nitro-containing pyrrolo[4,3,2- de ]quinolinones. 11 Wei and coworkers developed a radical bicyclization of 1,6-enynes with sulfonyl hydrazides to result in sulfone-featured polyheterocycles.…”