Radiation Therapy in the Management of Carcinoma of the Lung

Stereological estimates of the nuclear/cytoplasmic ratio and star volume on fibreoptic biopsies are of prognostic value for survival in a preliminary study of advanced squamous cell carcinoma of the lung

“…SqCC of the lung exhibits a very heterogeneous course and several studies have reported a large variation in survival after radiotherapy [7][8][9][10][11][12] . This may be, in part, due to differences in the lesion's malignant potential, thought to be associated with the degree of histological differentiation.…”

Multimodality treatment of non‐small cell lung cancer: Response to cisplatin, VP‐16, and 5‐FU chemotherapy and to surgery and radiation therapy

“…The treatment of patients staged to have unresectable stage 111 Mo without exploratory thoracotomy or at the time of thoracotomy is controversial and suboptimal. These patients are generally treated with external radiation therapy with a curative intent and have a median survival of about 9 months and a 5-year survival of about 5% [32-381. Even though most of these patients die of systemic metastases, a significant number die of progressive local disease [33,34]. This is of particular importance in squamous cell carcinoma, as shown by an autopsy series in which nearly one-half of the patients had no extrathoracic tumor and died because of a complication of intrathoracic tumor [36,37].…”