Radiation therapy for graves' ophthalmopathy: A retrospective analysis

Radiotherapy for Thyroid Orbitopathy

“…It is commonly known that the medial and inferior recti are preferentially infiltrated in Graves' orbitopathy. Eighty-five percent of our patients had improvement in their soft-tissue signs, and this percentage compared closely with the 80% reported by Petersen et al5 and the 76% reported by Palmer et al 12 We designed this study to quantify better the ef¬ fects of radiotherapy for Graves' orbitopathy on extra¬ ocular muscle restriction and strabismus. We demon¬ strated a statistically significant improvement in softtissue signs, supraduction, and both horizontal and vertical …”

Konventionelle und virtuelle Simulation bei der Retrobulbärbestrahlung

“…Im angloamerikanischen Raum werden hierfür vornehmlich bilaterale Gegenfelder mit einem Divergenzausgleich von 5°(SAD = 100 cm) empfohlen [6,16]. Bei einem Fokus-Isozentrum-Abstand von 100 cm und üblichen Feldgrößen beträgt die Strahldivergenz 1 bis 2°.…”

“…Die Überkompensation führt zu Dosisinhomogenitä-ten [21]. Als ventrale Feldgrenze wird von einigen Autoren der laterale knöcherne Kanthus (Processus frontalis ossis zygomatici) [6,16] angegeben. Bei allen von uns untersuchten Patienten führte allerdings diese Wahl der ventralen Feldbegrenzung zu unvollständiger Erfassung der Augenmuskeln.…”

Resection “en bloc” of the lateral wall and floor for decompression of the orbit in dysthyroid exophthalmos

“…It is safe to presume that most patients initially receive a treatment with corticosteroids, sometimes corn- Highly collimated super voltage radiation with the linear accelerator to the retro-orbital space is still advocated by some radiologists [8,34]. Notwithstanding all precautions, cataract, radiation retinopathy and optic atrophy leading to blindness have been reported [21].…”