Radiation therapy for exudative choroidal hemangioma

Finger, Paul T.

doi:10.4103/ijo.ijo_707_19

Cited by 9 publications

(5 citation statements)

References 22 publications

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“…Diffüz lezyon içinde sınırlı koroidal hemanjiyomu taklit eden lokal kalınlaşma alanları bulunabilir. 3,48 Tümör subretinal sıvı oluşturarak görme kaybına yol açabilir. Bu hemanjiyomlar konjenital olmalarına rağmen, retina dekolmanı adolesan dönem boyunca herhangi bir yaşta, ortalama 8 yaşında görülür.…”

Section: Diffüz Koroidal Hemanjiyomunclassified

Vascular Tumors and Malformations of the Choroid

ARTUNAY,

ÖZBEK,

MERT PEHLİVANOĞLU

2023

CRJ

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Choroidal vascular tumors; it may present as circumscribed and diffuse choroidal hemangiomas and rarely choroidal hemangiopericytoma and phacomatosis pigmentovascularis. Choroidal hemangiomas are benign vascular hamartomatous tumors that occur in two forms: circumscribed and diffuse. The circumscribed form is typically an isolated finding without systemic associations, while the diffuse form generally occurs in association with Sturge–Weber syndrome. Circumscribed choroidal hemangiomas are generally seen as well-circumscribed, round or oval, elevating dome-shaped orange or red masses located posterior to the equator in the fundus, whereas diffuse choroidal hemangiomas have a diffuse red-orange color appearance (tomatoketchup). Although the diagnosis of choroidal hemangioma is better investigated by means of multimodal imaging, indocyanine green angiography and ultrasonography are the most important tests in the differential diagnosis. For circumscribed choroidal hemangiomas with exudative retinal detachment or cystoid macular edema, a variety of treatment modalities are available. Symptomatic patients can be treated with oral propranolol, photodynamic therapy, transpupillary thermotherapy, plaque radiotherapy, external radiotherapy or intravitreal anti-vascular endothelial growth factors.In this review, the pathogenesis, clinical features and treatment methods in choroidal vascular tumors will be discussed.

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Section: Diffüz Koroidal Hemanjiyomunclassified

Vascular Tumors and Malformations of the Choroid

ARTUNAY,

ÖZBEK,

MERT PEHLİVANOĞLU

2023

CRJ

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“…[3] Management options include plaque brachytherapy (for circumscribed as well as to the nodular component if any, in the diffuse variant), photodynamic therapy or EBRT to halt tumor growth and control of subretinal fluid to achieve stabilization of visual acuity. [44,45] For control of IOP, medical management, transscleral cyclophotocoagulation, laser trabeculoplasty, MIGS, filtering or shunting surgeries can be performed.…”

Section: Choroidal Tumorsmentioning

confidence: 99%

Glaucoma Related to Ocular and Orbital Tumors

Yadav¹

2021

Ocular Hypertension - The Knowns and Unknowns

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Secondary glaucoma due to ocular and orbital tumors can be a diagnostic challenge. It is an essential differential to consider in eyes with a known tumor as well as with unilateral, atypical, asymmetrical, or refractory glaucoma. Various intraocular neoplasms including iris and ciliary body tumors (melanoma, metastasis, lymphoma), choroidal tumors (melanoma, metastasis), vitreo-retinal tumors (retinoblastoma, medulloepithelioma, vitreoretinal lymphoma) and orbital tumors (extra-scleral extension of choroidal melanoma or retinoblastoma, primary orbital tumors) etc. can lead to raised intraocular pressure. The mechanisms for glaucoma include direct (tumor invasion or infiltration related outflow obstruction, trabecular meshwork seeding) or indirect (angle closure from neovascularization or anterior displacement or compression of iris) or elevated episcleral venous pressure secondary to orbital tumors. These forms of glaucoma need unique diagnostic techniques and customized treatment considerations as they often pose therapeutic dilemmas. This chapter will review and discuss the mechanisms, clinical presentations and management of glaucoma related to ocular and orbital tumors.

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“…Radiation therapy has been used for benign choroidal and retinal vascular tumors 28,30,54 ; however, there exists no standard for radiation treatment of uveal leiomyomas. The literature suggests when irradiating muscle tissue, a dose <50 Gy would be tolerated.…”

Section: Radiationmentioning

confidence: 99%

Intraocular leiomyoma: Current concepts

Tomar

Finger

Iacob

2020

Survey of Ophthalmology

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leiomyoma actin melanoma immunohistochemistry benign uvea a b s t r a c tIntraocular leiomyoma is a benign smooth muscle tumor. First recognized before the era of immunohistochemistry, uveal leiomyomas have been described in case reports and small case series. We add 3 new cases, for a total of 80. Of these, there were 29 men and 51 women. The mean and median ages were 35.8 and 30.5 years respectively, with a range of 8 to 80 years. Curiously, ciliary body tumors were more common in females, whereas iris and posterior choroidal leiomyomas were more prevalent in males. Infrequently associated with systemic fibroids, nuclear expression of sex steroid receptors was inconsistent. Iris and posterior choroidal leiomyoma were predominantly amelanotic, while 40% of ciliary body leiomyomas were brown. Two-thirds of the leiomyomas blocked transillumination partially or completely, a feature shared by uveal melanoma. In general, low-frequency ultrasound imaging reveals low to moderate internal reflectivity; however, highfrequency anterior uveal ultrasound was used to localize a leiomyoma as resident in the suprachoroidal space with an overlying layer of intact choroid. In the few cases examined by physiologic imaging, increased metabolic activity (typically associated with malignancy and inflammation) has been noted. We found that pigmented uveal leiomyomas can be clinically identical to melanoma. Therefore, histopathology with immunohistochemical staining for smooth muscle actin was the most reliable diagnostic method to differentiate pigmented uveal leiomyoma from melanoma. Treatment is governed by the clinical diagnosis, tumor size and location, as well as prognosis for vision and globe preservation.

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Radiation therapy for exudative choroidal hemangioma

Cited by 9 publications

References 22 publications

Vascular Tumors and Malformations of the Choroid

Vascular Tumors and Malformations of the Choroid

Glaucoma Related to Ocular and Orbital Tumors

Intraocular leiomyoma: Current concepts

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