Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels

Mićić, Mileva; Milić, Tanja; Mitrić, Miodrag; Jokić, Bojan; Suljovrujić, E.

doi:10.1007/s00289-013-1026-9

Cited by 7 publications

(3 citation statements)

References 39 publications

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“…PVA/PVP-based hydrogels containing Ag NPs fabricated by Eid et al 72 were reported to be high, uniformly distributed, and stable. Poly(methacrylic acid) (PMAA) hydrogel reduced with borohydride by Bajpai et al 73 and poly(2-hydroxyethyl methacrylate/IA)/Ag NP hydrogels synthesized with gamma irradiation by Micic et al 74 showed antimicrobial activity against E. coli. The pHsensitive poly(methyl methacrylate-methacrylic acid)/Ag NP hydrogels synthesized with free radical cross-linking by Wei et al 75 can be potentially smart antimicrobial biomaterials.…”

mentioning

confidence: 99%

Antimicrobial hydrogels: promising materials for medical application

Yang

Han

Chen

et al. 2018

IJN

308

230

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The rapid emergence of antibiotic resistance in pathogenic microbes is becoming an imminent global public health problem. Local application of antibiotics might be a solution. In local application, materials need to act as the drug delivery system. The drug delivery system should be biodegradable and prolonged antibacterial effect should be provided to satisfy clinical demand. Hydrogel is a promising material for local antibacterial application. Hydrogel refers to a kind of biomaterial synthesized by a water-soluble natural polymer or a synthesized polymer, which turns into gel according to the change in different signals such as temperature, ionic strength, pH, ultraviolet exposure etc. Because of its high hydrophilicity, unique three-dimensional network, fine biocompatibility and cell adhesion, hydrogel is one of the suitable biomaterials for drug delivery in antimicrobial areas. In this review, studies from the past 5 years were reviewed, and several types of antimicrobial hydrogels according to different ingredients, different preparations, different antimicrobial mechanisms, different antimicrobial agents they contained and different applications, were summarized. The hydrogels loaded with metal nanoparticles as a potential method to solve antibiotic resistance were highlighted. Finally, future prospects of development and application of antimicrobial hydrogels are suggested.

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mentioning

confidence: 99%

Antimicrobial hydrogels: promising materials for medical application

Yang

Han

Chen

et al. 2018

IJN

308

230

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“…Some metals (Cu, Ag, Au, Pt) in the form of nanoparticles have antimicrobial properties [132]. It has been demonstrated that nanocomposite hydrogels containing Ag nanoparticles synthesized by γ-irradiation present an effective antimicrobial activity [44,49,133,134]. Ag NPs stabilized by PVA and synthesized by radiolysis possess a higher antibacterial activity than that of Ag NPs synthesized by other methods [45].…”

Section: Antimicrobial Propertiesmentioning

confidence: 99%

Synthesis of Metallic Nanostructures Using Ionizing Radiation and Their Applications

Remita,

Lampre

2024

Materials

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This paper reviews the radiation-induced synthesis of metallic nanostructures and their applications. Radiolysis is a powerful method for synthesizing metallic nanoparticles in solution and heterogeneous media, and it is a clean alternative to other existing physical, chemical, and physicochemical methods. By varying parameters such as the absorbed dose, dose rate, concentrations of metallic precursors, and nature of stabilizing agents, it is possible to control the size, shape, and morphology (alloy, core-shell, etc.) of the nanostructures and, consequently, their properties. Therefore, the as-synthesized nanoparticles have many potential applications in biology, medicine, (photo)catalysis, or energy conversion.

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“…The antimicrobial activity of hydrogel materials can be obtained relatively easily by dispersing the agent in acrylate monomer solutions or after polymerization, by immersing the hydrogel in an aqueous solution with an active agent . Another possibility is to conduct a reaction between monomers and an active agent to synthesize active copolymers .…”

Section: Introductionmentioning

confidence: 99%

Effects of antimicrobial agents on the thermal and mechanical properties of acrylate hydrogel matrices

Paillot

Jegat

Becquart

et al. 2016

J of Applied Polymer Sci

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International audiencePolymer materials with antimicrobial activity are prepared by UV polymerization of acrylate and methacrylate mixture at room temperature. The antimicrobials are silver acetate and copper (II) acetate, used without pretreatment. Their chemical stability in the acrylate matrix and their effect on the thermal and mechanical properties of the polymer matrix are investigated as a function of their concentration up to 15 wt%. Physico-chemical, thermal, rheological, and morphological analyses as well as the surveillance of metal salts release in aqueous medium are conducted. A significant decrease in the thermal stability of the salts introduced into the acrylate matrix is observed after UV treatment. The metal salts also have significant effects on the properties of the matrix. A plasticization and densification of the material associated with an aggregation of salts up to the percolation at the highest concentration are highlighted. At equal concentrations, the effects are more pronounced in the presence of copper salts. The latter was released more slowly than silver salts from acrylate material

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Radiation synthesis, characterisation and antimicrobial application of novel copolymeric silver/poly(2-hydroxyethyl methacrylate/itaconic acid) nanocomposite hydrogels

Cited by 7 publications

References 39 publications

Antimicrobial hydrogels: promising materials for medical application

Antimicrobial hydrogels: promising materials for medical application

Synthesis of Metallic Nanostructures Using Ionizing Radiation and Their Applications

Effects of antimicrobial agents on the thermal and mechanical properties of acrylate hydrogel matrices

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