Radiation Shielding Calculations for a 70- to 250-MeV Proton Therapy Facility

Hagan, W.K.; Colborn, B. L.; Armstrong, T. W.; Allen, M.

doi:10.13182/nse88-a22328

Cited by 12 publications

(4 citation statements)

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“…Currently these simulations have not been benchmarked against experimental measurements, but the neutron production observed agrees with what others reported previously. [31][32][33] …”

Section: Iib Monte Carlo Neutron Production Simulationsmentioning

confidence: 99%

“…34,35 The neutron energy spectra results presented here are similar to what others have reported for a proton beam stopping in a thick water and tissuelike target. [31][32][33] In the present work, the proposed DWA treatment system does not require any passive beam modification devices such as scattering foils, range modulators, or other devices used to deliver the proton beam to the patient. Hence, neutron production occurs principally in the stopping media.…”

Section: Iiib Neutron Productionmentioning

confidence: 99%

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Maximum proton kinetic energy and patient‐generated neutron fluence considerations in proton beam arc delivery radiation therapy

et al. 2009

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Several compact proton accelerator systems for use in proton therapy have recently been proposed. Of paramount importance to the development of such an accelerator system is the maximum kinetic energy of protons, immediately prior to entry into the patient, that must be reached by the treatment system. The commonly used value for the maximum kinetic energy required for a medical proton accelerator is 250 MeV, but it has not been demonstrated that this energy is indeed necessary to treat all or most patients eligible for proton therapy. This article quantifies the maximum kinetic energy of protons, immediately prior to entry into the patient, necessary to treat a given percentage of patients with rotational proton therapy, and examines the impact of this energy threshold on the cost and feasibility of a compact, gantry-mounted proton accelerator treatment system. One hundred randomized treatment plans from patients treated with IMRT were analyzed. The maximum radiological pathlength from the surface of the patient to the distal edge of the treatment volume was obtained for 180°continuous arc proton therapy and for 180°split arc proton therapy ͑two 90°arcs͒ using CT# profiles from the Pinnacle™ ͑Philips Medical Systems, Madison, WI͒ treatment planning system. In each case, the maximum kinetic energy of protons, immediately prior to entry into the patient, that would be necessary to treat the patient was calculated using proton range tables for various media. In addition, Monte Carlo simulations were performed to quantify neutron production in a water phantom representing a patient as a function of the maximum proton kinetic energy achievable by a proton treatment system. Protons with a kinetic energy of 240 MeV, immediately prior to entry into the patient, were needed to treat 100% of patients in this study. However, it was shown that 90% of patients could be treated at 198 MeV, and 95% of patients could be treated at 207 MeV. Decreasing the proton kinetic energy from 250 to 200 MeV decreases the total neutron energy fluence produced by stopping a monoenergetic pencil beam in a water phantom by a factor of 2.3. It is possible to significantly lower the requirements on the maximum kinetic energy of a compact proton accelerator if the ability to treat a small percentage of patients with rotational therapy is sacrificed. This decrease in maximum kinetic energy, along with the corresponding decrease in neutron production, could lower the cost and ease the engineering constraints on a compact proton accelerator treatment facility.

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“…Currently these simulations have not been benchmarked against experimental measurements, but the neutron production observed agrees with what others reported previously. [31][32][33] …”

Section: Iib Monte Carlo Neutron Production Simulationsmentioning

confidence: 99%

Section: Iiib Neutron Productionmentioning

confidence: 99%

Maximum proton kinetic energy and patient‐generated neutron fluence considerations in proton beam arc delivery radiation therapy

et al. 2009

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“…The protons beam used in radiation therapy is provided by two particle accelerators, cyclotrons, and synchrotrons, which produce proton beams at typical energies between 70 and 250 MeV [12]. The cyclotron, mainly used for proton therapy, is a machine which delivers protons with fixed energy.…”

Section: Accelerators Used In the Proton Therapymentioning

confidence: 99%

Interaction of proton beam with human tissues in proton therapy

Hazem

2023

Proton Therapy - Scientific Questions and Future Direction

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Proton therapy is an effective and safe method to treat tumors in human body. Instead of conventional radiation (X-rays), this technique uses a heavy charged particles (protons) to treat cancer. This chapter reviews the basic aspects of the physics of proton therapy, including proton beam properties, proton interaction mechanisms, and radiation effects induced in the human tissue. A more highly conformal technique of proton therapy called “pencil beam scanning”, based on intensity-modulated proton therapy (IMPT), will be also developed. The uncertainty in the determination of the relative biological effectiveness (RBE) will also be discussed in light of recent experimental results. We conclude the chapter by discussing future developments and potential challenges of proton therapy.

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“…Errors in these coefficients are not computed since the values listed by Hagen[54] und the parameters computed by Freeman[49] are stated without error. ........ = .............. i;/:1-ii .................. -6.0_o2;_1-20.0239-"i.i85 "................................................... 0;'................... 22°E nergy -Slope-............ tiiteic-ei, t............ Si0pe ............. h t, r pt....…”

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confidence: 99%

Shielding measurements for a 230 MeV proton beam

Siebers¹

1990

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This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or %, process disclosed, or represents that its use would not infringe privately owned rights. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise does not necessarily constitute or imply its endorsement, recom-% mendation, or favoring by the United States Government or any agency thereof. The views and opinions of authors expressed herein do not necessarily state or reflect those of the United States Government or any agency thereof.

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Radiation Shielding Calculations for a 70- to 250-MeV Proton Therapy Facility

Cited by 12 publications

References 1 publication

Maximum proton kinetic energy and patient‐generated neutron fluence considerations in proton beam arc delivery radiation therapy

Maximum proton kinetic energy and patient‐generated neutron fluence considerations in proton beam arc delivery radiation therapy

Interaction of proton beam with human tissues in proton therapy

Shielding measurements for a 230 MeV proton beam

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