Radiation recall dermatitis triggered by inactivated COVID‐19 vaccine

Afacan, Elif; Öğüt, Betül; Üstün, Petek; Senturk, Ertugrul; Yazici, O.; Adışen, Esra

doi:10.1111/ced.14786

Cited by 18 publications

(20 citation statements)

References 5 publications

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“…Soyfer et al reported two cases of RRP after administration of the Pfizer-BioNTech mRNA vaccine for a SARS-CoV-2 vaccine [ 4 ]. In addition, two cases with dermatitis of RRP occurred after administration of the Sinovac vaccine of inactivated virus vaccine and AstraZeneca of vector vaccine [ 3 , 10 ]. To the best of our knowledge, this is the first report of dermatitis of RRP after administration of the mRNA-1273 SARS-CoV-2 Vaccine (manufactured by Moderna).…”

Section: Discussionmentioning

confidence: 99%

Radiation recall phenomenon after administration of the mRNA-1273 SARS-CoV-2 vaccine

et al. 2022

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Several types of SARS-CoV-2 vaccine have been developed. However, the relationship between SARS-CoV-2 vaccine and radiation therapy (RT) is unclear. Recently, there have been some reports of radiation recall phenomenon (RRP) caused by a SARS-CoV-2 vaccine. We report a case of RRP after administration of the mRNA-1273 SARS-CoV-2 vaccine. A 51-year-old female was diagnosed with breast cancer (cT4N1M0, cStage IIIB) and underwent breast total mastectomy with axillary lymph node dissection after neoadjuvant chemotherapy. After mastectomy, the patient received RT with 50 Gy in 25 fractions. An acute side effect of grade 2 dermatitis according to the National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0. occurred after RT. The patient had not started any new systemic medication after RT; however, the patient received the mRNA-1273 SARS-CoV-2 vaccine (Moderna) 1 month after the end of the initial RT. Seven days after vaccination, the patient had a skin reaction with burning sensation and redness. This skin reaction was induced in an area corresponding to the irradiation field of the chest wall. There was no skin reaction in areas other than that described. The reaction was cured within 1 week with topical hydrocortisone. This report is an interesting case report with a RPP after administration of the mRNA-1273 SARS-CoV-2 vaccine.

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Section: Discussionmentioning

confidence: 99%

Radiation recall phenomenon after administration of the mRNA-1273 SARS-CoV-2 vaccine

et al. 2022

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“…Few reports of RRD after COVID‐19 vaccination have been recently published. 3 , 4 , 5 The radiation recall reactions occurred after the adenovirus vector vaccine (Oxford‐AstraZeneca, UK), 5 inactivated virus vaccine (Sinovac Coronavac, China), 3 and RNA virus vaccine (Moderna, USA). 4 Our case developed radiation recall dermatitis after injection of an inactivated virus vaccine (Sinopharm, China).…”

Section: Discussionmentioning

confidence: 99%

“…Recently, a few cases of RRD have been reported after different types of COVID‐19 vaccine in the skin and lung. 3 , 4 , 5…”

Section: Introductionmentioning

confidence: 99%

COVID‐19 vaccine‐induced Radiation Recall Dermatitis: Report of a case

Sepaskhah

Asl

Taheri

et al. 2022

Clinical Case Reports

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“…The few available reports suggest that this vaccine can induce the radiation recall phenomenon. 1 , 2 Cole et al also reported a case of radiation recall pneumonitis after anti‐COVID vaccination. 3 In our case, nothing other than the COVID‐19 vaccine was administered after the last CT examination, so the vaccine must have been related to the onset of this case of radiation recall pneumonitis.…”

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confidence: 98%