Radiation necrosis and therapeutic outcomes in patients treated with linear accelerator‐based hypofractionated stereotactic radiosurgery for intact intracranial metastases
Abstract:Introduction: Balancing disease control and treatment-related toxicities can be challenging when treating higher-risk brain metastases (BMs) that are larger in size or eloquent anatomical locations. Hypofractionated stereotactic radiosurgery (hfSRS) is expected to offer superior or equal efficacy with lower toxicity profile compared with single-fraction SRS (sfSRS). We report the efficacy and toxicity profiles of hfSRS in a consecutive cohort of patients to support this predicted benefit from hfSRS for high-ri… Show more
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