Radiation gastritis after Yttrium-90 radioembolization

Abstract

Tuberculosis is an insidious infection that has followed human beings for centuries. Esophageal disease is an importation presentation of extrapulmonary tuberculosis that results from the proximity of pulmonary lymph nodes to the middle esophagus. It develops as a secondary infection due to mycobacterial lymphatic spread, rather than a primary infection. Mycobacterium tuberculosis complex is the most common agent seen, but M abscessus, chelonae, and avium complex have been reported. The symptoms most frequently reported are dysphagia and noncardiac chest pain. Endoscopic evaluation generally shows mucosal ulcerations (56%) or an extrinsic bulge in the middle third of the esophagus (62%).

Yttrium-90-Induced Gastropathy: A Potential Equivocal Finding

“…Gastrectomy could be considered for refractory cases. [1-3]. Due to its potential puzzling effect regarding clinical and endoscopic features, it is important for endoscopists to always consider this differential diagnosis in patients presenting with abdominal pain and previous history of radioembolization therapy.…”

Gastrointestinal Tract Injury by Yttrium-90 Appears Largely Restricted to Resin Microspheres But Can Occur Years After Embolization

“…Despite a notable incidence of gastrointestinal complications, the histopathologic features associated with this nontargeted delivery have not been thoroughly examined. Prior publications consist of either solitary case reports or limited series of up to 5 patients 5–10. The primary purpose of this study is to assess the pathologic sequela of biopsy-proven gastrointestinal injury secondary to Y90 therapy in a larger multi-institutional cohort.…”