Radiation Exposure During Transarterial Chemoembolization: Angio-CT Versus Cone-Beam CT

Piron, Lauranne; Roy, Julien Le; Cassinotto, Christophe; Delicque, Julien; Belgour, A.; Allimant, Carole; Beregi, Jean‐Paul; Greffier, Joël; Molinari, Nicolas; Guiu, Boris

doi:10.1007/s00270-019-02269-8

Cited by 31 publications

(21 citation statements)

References 36 publications

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“…Common CT scanning methods in clinic include routine scanning and enhanced scanning. Among them, the enhanced scan introduces a contrast agent into the body to enhance the contrast of the observed object, and it is easy to distinguish the lesion area [2]. CT contrast agents currently used clinically are mainly iodine contrast agents; however, large doses of iodine can cause harm to the human body.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Development Mechanism of Giant Cell Arteritis in Nude Mouse Model through Color Duplex Sonography and Computerized Tomography Nanocontrast Agent

Chen

Zhou

et al. 2021

BioMed Research International

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To explore the application value of color duplex sonography and enhanced computerized tomography (CT) inspection based on a nanocontrast agent in diagnosis and pathogenesis in giant cell arteritis (GCA), the GCA nude mouse model was constructed. In this study, 40 healthy male BalB/c nude mice aged 6-8 weeks were randomly divided into a control group (no model) and an experimental group (model), with 20 mice in each group, and the temporal artery tissue of GCA patients diagnosed as positive by temporal artery biopsy was implanted into nude mice to construct a GCA nude mouse model. Abdominal aortic biopsy and immunohistochemistry were used to verify the success of the GCA nude mouse model. All nude mice were subjected to color duplex sonography and enhanced CT examination based on a nanocontrast agent. At the same time, the basic indicators such as body weight, temperature, white blood cell (WBC), lymphocytes (LYM), hemoglobin (HGB), and platelet (PLT) were measured, and the protein expression levels of interleukin-6 (IL-6) and signal transducer and activator of transcription 3 (STAT3) were detected by immunohistochemistry. The results showed that the temporal artery wall of the nude mice in the experimental group thickened and the lumen was significantly narrowed, indicating that the cell arteritis model of nude mice was successfully constructed; ultrasound examination showed that the right superficial temporal artery vascular cavity narrowed, the blood flow signal changed like a filling defect around the periphery, and there was a low echo halo. CT examination showed that the left superficial temporal artery narrowed, and the inner diameter of the narrow segment of blood vessels changed like a bead. The body weight of nude mice in the experimental group decreased significantly after the modeling was completed ( P < 0.05 ); after modeling, the body temperature of the nude mice in the experimental group increased significantly ( P < 0.05 ); LYM and HGB values of nude mice in the experimental group were significantly lower than those in the control group ( P < 0.05 ); the content of IL-6, STAT3, IL-6, and STAT3 proteins in the arterial tissue of nude mice in the experimental group was lower than that of the control group ( P < 0.05 ), indicating that color duplex sonography and CT contrast agent technology can be used in the diagnosis and development mechanism research of GC.

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Section: Introductionmentioning

confidence: 99%

Analysis of Development Mechanism of Giant Cell Arteritis in Nude Mouse Model through Color Duplex Sonography and Computerized Tomography Nanocontrast Agent

Chen

Zhou

et al. 2021

BioMed Research International

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“…In recent years, the efficacy and safety of percutaneous ablation for RAML have been gradually confirmed (1,7,8). The introduction and clinical application of angio-computed tomography (angio-CT) devices have enabled the integration of SAE and radiofrequency ablation (RFA), improved imaging quality, and made operations simpler and safer (9,10). The present study retrospectively analyzed the results from 6 patients with RAML treated with SAE+RFA, to evaluate the feasibility, safety, and efficacy of this new combination approach.…”

Section: Introductionmentioning

confidence: 99%

A new management strategy for renal angiomyolipomas: superselective arterial embolization in combination with radiofrequency ablation

Liu

Tang

et al. 2019

Ann Transl Med

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Background: The present study analyzed the safety and efficacy of superselective arterial embolization (SAE) combined with radiofrequency ablation (RFA) to treat renal angiomyolipoma (RAML).Methods: This retrospective study included the clinical data of 6 patients with RAML treated between March 2016 and October 2017. All patients underwent RFA treatment immediately after SAE guided by angio-computed tomography (angio-CT). The tumor size, renal function and complications, and time to recurrence were compared before and after treatment. Results:The success rate of the SAE + RFA technique was 100%, and no serious complications were found during or after surgery. After treatment, the patients' symptoms, including low back pain and hematuria, were relieved. The pre-treatment creatinine level (55.6±11.0 μmol/L) did not differ significantly from the post-treatment creatinine level (68.2±13.7 μmol/L), which was measured 1 day after surgery (t=1.75, P=0.109). The mean follow-up time was 29.5±6.1 months. By the end of the follow-up period, the maximum diameter of the tumor was 3.1±0.6 cm, which was significantly smaller than the pre-treatment diameter of 5.9±1.01 cm (t=5.83, P<0.001). At 3 months after surgery, the maximum diameter of the tumor was reduced by 22-38% in all 6 patients. At the last follow-up examination, the maximum diameter of the tumor was reduced by 36-61%. Contrast-enhanced CT or magnetic resonance imaging scans showed that the enhanced part of the original lesion had disappeared, the renal parenchyma was full of even fat signals, and only one patient had new enhanced lesions at the site of the original lesions.Conclusions: SAE combined with RFA is a safe and effective treatment for RAML, and its strengths qualify it to become a new treatment strategy for RAML.

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“…In CBCT, these factors are also procedure (ie, projection) specific (31). According to a recent study, the radiation dose of angio-CT is less than the radiation dose of CBCT when automatic exposure control is used (32). If noise levels are matched between angio-CT and CBCT, the radiation dose is approximately the same for angio-CT and CBCT.…”

Section: Comparison With Cbctmentioning

confidence: 99%

Combined Angio-CT Systems: A Roadmap Tool for Precision Therapy in Interventional Oncology

Taiji¹,

Lin²,

Lin³

et al. 2021

Radiology: Imaging Cancer

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Combined angiography-CT (angio-CT) systems, which combine traditional angiographic imaging with cross-sectional imaging, are a valuable tool for interventional radiology. Although cone-beam CT (CBCT) technology from flat-panel angiography systems has been established as an adjunct cross-sectional imaging tool during interventional procedures, the intrinsic advantages of angio-CT systems concerning superior soft-tissue imaging and contrast resolution, along with operational ease, have sparked renewed interest in their use in interventional oncology procedures. Owing to increases in affordability and usability due to an improved workflow, angio-CT systems have become a viable alternative to stand-alone flat-panel angiographic systems equipped with CBCT. This review aims to provide a comprehensive technical and clinical guide for the use of angio-CT systems in interventional oncology. The basic concepts related to the use of angio-CT systems, including concepts related to workflow setup, imaging characteristics, and acquisition parameters, will be discussed. Additionally, an overview on the clinical applications and the benefits of angio-CT systems in routine therapeutic and palliative interventional oncology procedures will be reviewed.

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Radiation Exposure During Transarterial Chemoembolization: Angio-CT Versus Cone-Beam CT

Cited by 31 publications

References 36 publications

Analysis of Development Mechanism of Giant Cell Arteritis in Nude Mouse Model through Color Duplex Sonography and Computerized Tomography Nanocontrast Agent

Analysis of Development Mechanism of Giant Cell Arteritis in Nude Mouse Model through Color Duplex Sonography and Computerized Tomography Nanocontrast Agent

A new management strategy for renal angiomyolipomas: superselective arterial embolization in combination with radiofrequency ablation

Combined Angio-CT Systems: A Roadmap Tool for Precision Therapy in Interventional Oncology

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