Radiation dose in interventional cardiology

Tsapaki, Virginia

doi:10.2217/iim.10.20

Cited by 9 publications

(9 citation statements)

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“…Tissues in developing years in pediatric age group are radiosensitive [49]. Further, it is to be noted that children have small body surface area and their lungs are not far from their sites of radiation fields even if not direct to it, so they are susceptible to the effect of irradiation because of their small body proportions.…”

Section: Pulmonary Functions In Pediatric Cancer Survivors mentioning

confidence: 99%

Pulmonary Complications in Survivors of Childhood Hematological Malignancies: Single-Center Experience

Tantawy¹,

Elbarbary²,

Ahmed³

et al. 2011

Pediatric Hematology and Oncology

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Children treated for cancer face the risk of complications later in life, including pulmonary dysfunction. The objective of this study was to evaluate frequency and severity of pulmonary complications in survivors of childhood leukemia and lymphoma treated with chemotherapy alone or combined with radiotherapy. Seventy cancer survivors of hematological malignancies were evaluated for pulmonary complications through history taking, chest examination, high-resolution computed tomography (HRCT) chest, and pulmonary function testing (PFTs). Although most survivors were not clinically compromised, the spectrum of impaired PFTs included obstructive pattern (14.3%), restrictive pattern (5.7%), and mixed pattern (20%). Significant pulmonary dysfunction was seen in children older than 10 years of age (P = .003), and in patients treated with combined chemotherapy and radiotherapy (72.7%) compared with those treated with chemotherapy alone (25%) (P = .001). Cumulative dose of bleomycin was significantly associated with abnormal PFTs (P = .04). Multivariate analysis revealed methotrexate therapy as significant predictor of abnormal PFTs (P = .002). Male patients who received combined therapy showed higher frequency of restrictive, obstructive lung disease, abnormal respiratory reactance, and peripheral airway disease (P = .007, P = .04, P = .002, P = .003, P = .05, respectively). Those with abnormal CT findings (n = 14) had lower forced vital capacity (FVC%), forced expiratory volume in 1 second (FEV(1)%), and peak expiratory flow (PEF%) when compared to cases with normal CT (P = .001, P< 0.001, P = .001, respectively). Subclinical pulmonary function abnormalities are found in survivors of childhood hematological malignancies previously treated and off therapy. Pulmonary dysfunction is more evident with combined chemotherapy and radiotherapy, bleomycin, and methotrexate are the most incriminated chemotherapeutic agents, and males are at higher risk than females; therefore a specific and extended follow-up is warranted.

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Section: Pulmonary Functions In Pediatric Cancer Survivors mentioning

confidence: 99%

Pulmonary Complications in Survivors of Childhood Hematological Malignancies: Single-Center Experience

Tantawy¹,

Elbarbary²,

Ahmed³

et al. 2011

Pediatric Hematology and Oncology

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“…O ne of the diagnostic and treatment methods for heart diseases is using ionizing radiation, which has quickly made progress recently. Interventional procedures have become more common in most countries owing to their prosperous clinical results and improved patients' safety [1,2].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Patient Dose with Special Look at Pediatrics during Cardiovascular Imaging

2018

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Aim: During interventional cardiology processes, patients especially women and children receive high radiation doses due to their sensitivities. In this study, we evaluated a pediatric patient dose separately in those undergone intervention cardiac procedure.Methods: In a public hospital with 252 patients, Entrance Skin Dose (ESD) and Dose-Area Product (DAP) were recorded. Prior to the beginning of fluoroscopic procedure, the chest thickness and Body Mass Index (BMI) of patients were measured. Furthermore, kV, mAs, an angle of tube and time of angiography and angioplasty were recorded.Results: Children ratio to all patients underwent the cardiovascular imaging was 1.8. The means of patients' ESD, DAP and fluoroscopy time were 178.3±17 mGy, 1123.6±11 μGym2 and 281.4±181.2 s, respectively for coronary angiography. In coronary angioplasty, the increase in ESD, DAP and fluoroscopy times were observed. In children with congenital heart disease, ESD mean, DAP and fluoroscopy time were 24.0±9.8 mGy, 147.8±62 μGym2, and 552±72s, respectively. The females were 96.8 under 30 years and their dose mean was 276±37 mGy, 368±24 μGym2 for ESD and DAP received, respectively with 376s fluoroscopy time. More than 37% of patients had (25-30) BMI. The relation between the patients’ BMI and DAP was significant (p=0.0001). Mean mAs was 359±34 and kV was 71.23±2.7. Above all, a direct and significant correlation was found between the patients’ chest thickness with variation kV (p=0.037, r=0.11) and mAs (p<0/001, r =0/28).Conclusion: The results demonstrated that the number of children referred to the cardiologic part of the heart and the also dose rate received by them during this test were higher than the data provided for children in developing countries, thus the factors causing such diseases require more attention. Moreover, the number of women was more than twice the referred patients to the heart imaging center, the doses received by these women can be causes of maternal diseases in children. Paying attention to the children's perception of high-fluorescence time is necessary in comparison with total angiography time in order to reduce the number of radiation injuries among pediatrics.

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“…PCI is a non-surgical procedure used to open significantly narrowed or blocked coronary arteries and restore arterial blood flow to the heart tissue. Over the past few decades, the number of IC procedures has been steadily increasing for the following reasons: improvement in X-ray equipment, enhanced cardiologists' clinical skill levels, and advances in stent technologies (1)(2)(3). Nowadays, interventional cardiologists perform more complex PCI procedures which were previously impossible or required open surgery.…”

mentioning

confidence: 99%

“…Thus, the risk of stochastic and deterministic radiation effects grows. ED is the most appropriate quantity for estimating stochastic radiation risk and comparing radiation doses across various medical examinations (1,6,7) . According to the International Commission on Radiological Protection (ICRP) 119, ED is equal to the sum of the weighted equivalent doses in all tissues and organs of the body (8) .…”

mentioning

confidence: 99%

“…According to the International Commission on Radiological Protection (ICRP) 119, ED is equal to the sum of the weighted equivalent doses in all tissues and organs of the body (8) . In practice, it is difficult to determine ED during IC procedures, as the measured radiation dose in 12 organs is required (1) . In literature, ED has been calculated using various methods in cardiac intervention procedures (9)(10)(11)(12) .It is necessary to reduce radiation exposure of patients in PCI procedures, while still keeping an appropriate image quality.…”

mentioning

confidence: 99%

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Comprehensive assessment of radiation dose in patients undergoing percutaneous coronary intervention: the effect of beam angulation on patient dose optimization

et al. 2021

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Comprehensive assessment of radiation dose inpatients undergoing percutaneous coronary intervention: the effect of beam angulation on patient dose optimization INTRODUCTIONIC procedures play an important role in the diagnosis and treatment of heart diseases. PCI is a non-surgical procedure used to open significantly narrowed or blocked coronary arteries and restore arterial blood flow to the heart tissue. Over the past few decades, the number of IC procedures has been steadily increasing for the following reasons: improvement in X-ray equipment, enhanced cardiologists' clinical skill levels, and advances in stent technologies (1)(2)(3). Nowadays, interventional cardiologists perform more complex PCI procedures which were previously impossible or required open surgery.

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Radiation dose in interventional cardiology

Cited by 9 publications

References 54 publications

Pulmonary Complications in Survivors of Childhood Hematological Malignancies: Single-Center Experience

Pulmonary Complications in Survivors of Childhood Hematological Malignancies: Single-Center Experience

Assessment of Patient Dose with Special Look at Pediatrics during Cardiovascular Imaging

Comprehensive assessment of radiation dose in patients undergoing percutaneous coronary intervention: the effect of beam angulation on patient dose optimization

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