Radiation and Health Effects

Ray, Kausik K.; Stick, Melissa

doi:10.1016/b978-0-12-800159-2.00032-4

Cited by 5 publications

(1 citation statement)

References 77 publications

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“…[18][19][20][21][22] This is hormesis, a phenomenon in which a harmful substance gives beneficial effects at a low concentration. 23 At a relatively low concentration, ROS will stimulate extra Calcium (Ca 2+ ) release from the sarcoplasmic reticulum of myocytes. 24 Ca 2+ binds to the Ccomponent of the actin-filament in sarcomeres, exposing the binding site for the myosin head which generates a cross-bridge and stimulates muscle contraction.…”

Section: Introduction the Effect Of Varying Eccentric Velocity On Mus...mentioning

confidence: 99%

The Effect of Varying Eccentric Velocity on Muscle Hypertrophy

Amjad

Dumont

2023

Sciential

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Resistance training is essential to muscle hypertrophy as it fatigues fibres through time-under-tension (TUT). As myocyte energy depletes, metabolites accrete, leading to inflammation to increase cell size, so it is adapted for future stimuli. TUT can be measured by varying eccentric velocities: i.e., the rate at which a muscle lengthens under load. A longer period of lengthening will lead to greater metabolite accretion and inflammation. However, it is unknown whether TUT is a threshold or if it can gradually increase and lead to more muscle growth. Through a literature review and experiment, this project investigates the effect of varying eccentric velocity on muscle hypertrophy. Previous research in the field of muscle physiology and metabolism were explored, with an emphasis on eccentric training. The supplementary experiment measured shoulder growth in response to the medial deltoid exercise called lateral raises, where different eccentric velocities were assigned to groups. Individualistic daily calorie and protein intake were controlled to ensure that sufficient nutrients were available for recovery and performance. Surprisingly, post-experimental research suggested that high-velocity eccentric training was best for hypertrophy due to greater levels of force production. This was consistent with the experiment, which found that the group with a fast-velocity eccentric, a lower TUT, experienced greater growth. They also exhibited greater strength gain due to neuromuscular junction adaptation. These findings related to TUT are significant for designing exercise regimens that are optimal for the prevention and rehabilitation of musculoskeletal injuries and disorders. The review’s findings suggest that fast-velocity eccentric contractions are ideal for increasing muscle size and strength.

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