2011
DOI: 10.1016/j.juro.2011.07.111
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Racial Variation in Timing of Pyeloplasty: Prenatal Versus Postnatal Diagnosis

Abstract: Purpose We have previously shown that non-white patients with UPJ obstruction undergo pyeloplasty at a younger age than do whites. The mechanisms behind this are unclear, as there is no known racial variation in the natural history of UPJ obstruction. We sought to use a detailed clinical database to explain this phenomenon. Methods We performed a retrospective review of all patients undergoing primary pyeloplasty at our institution between 1992 and 2008. Over 360 data points were abstracted for each patient,… Show more

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Cited by 5 publications
(7 citation statements)
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References 14 publications
(12 reference statements)
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“…However, race has not been previously well examined as a predictor of outcomes in pediatric urology, with studies either excluding race from their analyses 38 for unclear 6 reasons or being limited, by the data sets used, to exploring associations with timing of surgery rather than with complications. [39][40][41] Additionally, multiple risk score nomograms in the pediatric surgery literature did not specifically assess race as a predictor of outcomes, [42][43][44] which highlights the clinical importance of our finding.…”
Section: Discussionmentioning
confidence: 88%
“…However, race has not been previously well examined as a predictor of outcomes in pediatric urology, with studies either excluding race from their analyses 38 for unclear 6 reasons or being limited, by the data sets used, to exploring associations with timing of surgery rather than with complications. [39][40][41] Additionally, multiple risk score nomograms in the pediatric surgery literature did not specifically assess race as a predictor of outcomes, [42][43][44] which highlights the clinical importance of our finding.…”
Section: Discussionmentioning
confidence: 88%
“…Previous work conducted by Chu et al found that Black children had a statistically significant higher odds ratio of having postoperative complications following pediatric urologic procedures [ 13 ]. Conversely, multiple studies have documented that non-White children tend to have an earlier surgical intervention for ureteropelvic junction obstruction when presenting postnatally [ 14 - 16 ]. Among their findings, Routh et al also found that non-White patients were more likely to have surgery in the first year of life.…”
Section: Discussionmentioning
confidence: 99%
“…Among their findings, Routh et al also found that non-White patients were more likely to have surgery in the first year of life. They posited that this might be due to decreased access to prenatal care causing more emergent surgery to be warranted [ 14 ]. Although not seen in our linear model, our bivariate analysis aligns with their previous findings that Black patients tend to have a shorter time to surgery intervals than White patients.…”
Section: Discussionmentioning
confidence: 99%
“…Notably, a prior study determined that the racial difference in pyeloplasty timing is limited to children who present after birth. 9 Our patient population was overwhelmingly diagnosed prenatally, potentially eliminating the source of racial variation and likely reflecting the growing prevalence of prenatal diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…This lack of uniform guidelines may also be associated with previously described demographic variations in the timing of pyeloplasty. 8,9 These studies raise the potential for racial differences in the natural history of suspected UPJO or true demographic health disparities. However, the absence of detailed clinical data or an observational control group in these studies limits the ability to determine their true impact.…”
Section: Introductionmentioning
confidence: 99%