Racial/Ethnic Differences in Functional Outcomes in the 5 Years After Diagnosis of Localized Prostate Cancer

Johnson, Terri; Gilliland, Frank D.; Hoffman, Richard M.; Deapen, Dennis; Penson, David F.; Stanford, Janet L.; Albertsen, Peter C.; Hamilton, Ann S.

doi:10.1200/jco.2004.09.127

Cited by 64 publications

(76 citation statements)

References 29 publications

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“…African-American men reported greater rates of loss of desire following treatment, but they had more positive attitudes about help seeking. A 5-year prospective study reported by Johnson et al 47 surveyed 1475 nonHispanic white, 321 African-American and 279 Hispanic prostate cancer patients on their urinary, bowel and sexual functioning. At 60-month followup, radiation patients of all ethnic groups reported fairly similar outcomes.…”

Section: Resultsmentioning

confidence: 99%

The psychosocial aspects of sexual recovery after prostate cancer treatment

et al. 2009

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Prostate cancer affects one in six American men. Erectile and sexual dysfunctions are long-term side effects of prostate cancer treatment. PubMed database was searched for papers on prostate cancer-related sexual recovery for men and couples. The search yielded articles on (1) the treatment of erectile dysfunction, (2) men's psychological and culturally diverse adaptation to the sexual side effects; (3) the impact of prostate cancer on couples' relationships; and (4) interventions to promote sexual function. Erectile dysfunction after prostate cancer treatment has been widely studied.Research on the sexual recovery of men and couples or understanding it in a cultural context is scarce. Greater focus on the impact of sexual sequelae of prostate cancer treatment on men as well as couples in diverse groups is needed. Clinical implications for treating sexual dysfunction and promoting sexual recovery for prostate cancer survivors and their partners are discussed. Recommendations for future research are provided.

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Section: Resultsmentioning

confidence: 99%

The psychosocial aspects of sexual recovery after prostate cancer treatment

et al. 2009

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“…4,5 Previously, we detailed HRQOL recovery in Japanese men with localized prostate cancer followed for 2 years after RP. 6 In the current analysis we assessed temporal changes in HRQOL up to 5 years following RP using validated questionnaires.…”

Section: Introductionmentioning

confidence: 99%

Quality of life after radical prostatectomy in Japanese men: A 5‐Year follow up study

Namiki¹,

Ishidoya²,

Ito³

et al. 2008

Int J of Urology

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Objectives: To measure health-related quality of life (HRQOL) after radical prostatectomy (RP) in Japanese men with localized prostate cancer. Methods: A total of 154 patients who underwent RP were included in this 5-year longitudinal survey. The Short Form 36-Item Health Survey, the University of California, Los Angeles, Prostate Cancer Index and the International Prostate Symptom Score questionnaires were administered at diagnosis and nine times afterwards. Results: Patients undergoing RP showed problems in some physical domains of general HRQOL, but these problems diminished over time. Mental health and social functions significantly improved during the follow-up period. The urinary function substantially declined at 3 months and continued to recover gradually but never returned to baseline. Most patients (95%) recovered to their baseline urinary bother score within 60 months. The overall mean total International Prostate Symptom Score progressively improved with time. On the other hand , at 60 months after RP, only 34% of subjects had fully returned to baseline sexual function. By 5 years postoperatively, 78% of the men had reached baseline sexual bother and the mean recovery time was 8.6 months. Adverse effects of RP on sexual function and bother were mitigated by bilateral nervesparing procedures up to 5 years after the operation. Conclusions: Despite reported problems with sexuality and urinary continence, general HRQOL was mostly unaffected by RP after 6 months in our survey with functional outcomes remaining relatively stable in the majority of patients.Key words: longitudinal study, prostate cancer, quality of life, radical prostatectomy. IntroductionCurrently, the most common therapeutic options for localized prostate cancer are radical prostatectomy (RP), external radiation, and interstitial brachytherapy. RP is considered an especially safe and effective treatment for localized prostate cancer and has gained popularity among Japanese urologists over the last decade.1 As prostate cancer is increasingly diagnosed at early stages and therefore with more favorable survival outcomes, the basis on which patients select primary therapy has shifted toward considerations of health-related quality of life (HRQOL). 2,3Accordingly, HRQOL assessment has become an important form of outcome-based research that may weigh heavily on the justification of health care expenditures and the treatment selection by patients.Several assessments of HRQOL after prostate cancer treatment have been limited to studies of non-Hispanic whites, African-Americans, and Hispanics in the USA.4,5 Previously, we detailed HRQOL recovery in Japanese men with localized prostate cancer followed for 2 years after RP. 6 In the current analysis we assessed temporal changes in HRQOL up to 5 years following RP using validated questionnaires. To our knowledge the current study is the longest-term prospective study to assess the impact of RP on general and disease-specific outcomes following RP in Japanese men with clinically localized prostate can...

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“…1,5,20,21 Despite the importance of this work, there has been little effort to examine if a better understanding of the consequences that commonly result from managing early-stage prostate cancer translate into better recognition and management of functional and quality-of-life deficits or to improvements in the survivorship experience. A major barrier to achieving this goal has been the failure to incorporate patient-reported QOL widely into clinical practice.…”

Section: Discussionmentioning

confidence: 99%

Quality of life and satisfaction among prostate cancer patients followed in a dedicated survivorship clinic

Gilbert

Dunn

Wittmann

et al. 2014

Cancer

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BACKGROUND: Integrating quality-of-life (QOL) outcomes into clinics may assist providers in identifying and responding to problems experienced by cancer survivors. To date, however, patient-reported outcomes (PROs) such as QOL are used infrequently to guide care. We integrated QOL assessments into a prostate cancer survivorship clinic and compared recovery and satisfaction among men managed in the survivorship clinic with those followed with more routine care. METHODS: We conducted a before-after study comparing 235 men treated surgically for prostate cancer who received routine follow-up care with 102 men managed in a survivorship clinic characterized by point-of-care QOL reporting and integration of QOL scores (EPIC) following radical prostatectomy. We then assessed baseline and postprostatectomy QOL at 6 and 12 months, as well as patient satisfaction, and compared outcomes between groups. RESULTS: Although baseline QOL was comparable, scores were generally higher among the survivorship group at 6 months and 1 year compared with those followed with routine care. In particular, sexual function scores were significantly higher among patients managed in the survivorship clinic (52.2 vs 33.6 at 1 year, P <.01). Satisfaction scores were consistently higher in the survivorship clinic group compared with the routine-care group (all P <.05). CONCLUSIONS: Patient QOL and satisfaction were higher among men managed in a survivorship program, suggesting that disease-specific survivorship clinics that integrate QOL reporting into care pathways may yield better outcomes compared with less tailored approaches to patient care following cancer therapy. Cancer 2015;121:1484-91. V C 2014 American Cancer Society.KEYWORDS: prostate cancer, survivorship care, quality of life assessment. INTRODUCTIONAlthough most men treated for localized prostate cancer experience favorable cancer outcomes, treatment is often associated with lasting functional and quality-of-life (QOL) impairments. For example, men treated surgically (prostatectomy) face a 10%-15% risk of problematic urinary incontinence and greater than 50% risk of erectile dysfunction. 1,2 Radiation therapy is associated with similar QOL deficits, including sexual dysfunction, exacerbation of obstructive urinary symptoms, and bothersome bowel symptoms. 3-5 As a result, there has been long-standing interest in assessing quality-of-life outcomes among this patient population. However, prior efforts in this area have been primarily research oriented, focusing on instrument development, measurement and assessment of treatment-related consequences. Relatively little work has focused on integrating or translating QOL outcomes into clinical settings to guide patient care, in part because of a lack of available point-of-care tools to collect, score, and interpret patient-reported outcomes during clinic visits. Other barriers limiting the use of QOL in clinical care include logistical issues, such as lack of provider time to track functional outcomes or use them to guide interventions. As...

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Racial/Ethnic Differences in Functional Outcomes in the 5 Years After Diagnosis of Localized Prostate Cancer

Cited by 64 publications

References 29 publications

The psychosocial aspects of sexual recovery after prostate cancer treatment

The psychosocial aspects of sexual recovery after prostate cancer treatment

Quality of life after radical prostatectomy in Japanese men: A 5‐Year follow up study

Quality of life and satisfaction among prostate cancer patients followed in a dedicated survivorship clinic

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