Racial/ethnic and socioeconomic disparities in the use of newer diabetes medications in the Look AHEAD study

Elhussein, Ahmed; Anderson, Andrea; Bancks, Michael P.; Coday, Mace; Knowler, William C.; Peters, Anne L.; Vaughan, Elizabeth M.; Maruthur, Nisa M.; Clark, Jeanne M.; Pilla, Scott J.

doi:10.1016/j.lana.2021.100111

Cited by 34 publications

(34 citation statements)

References 29 publications

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“…1,2,3,4,5 Underrepresentation of Spanish speakers in research limits subgroup analyses to determine whether treatments are effective for this population, which exacerbates health inequity, 6 especially in type 2 diabetes care in the United States. 7 By underrepresented, we mean that participation of individuals from racial, ethnic, or linguistic groups is not proportional to their share of the population meant to benefit from trial findings. For instance, in adult vaccine trials reporting racial/ethnic participation data, Hispanics composed 11.6% of trial participants (as low as 3% in cancer clinical trials), 6 although they constituted 18.5% of the US adult population in 2019.…”

Section: Underrepresentation Exacerbates Inequitymentioning

confidence: 99%

How Should Representation of Subjects With LEP Become More Equitable in Clinical Trials?

Alhalel

Francone

Post

et al. 2022

AMA Journal of Ethics

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Underrepresentation of individuals with limited English proficiency (LEP) who speak Spanish is ongoing in phase 3 biomedical clinical trials and exacerbates health inequity. This article suggests strategies for increasing representation of Spanish speakers in clinical rials by emphasizing the importance of early engagement with Spanish language communities, inclusive participant recruitment, and collaborative trial design and implementation. Although investigators and institutions administering government-funded research must meet federal requirements for language assistance, journal editors, peer reviewers, institutional review board members, academic health centers, and all beneficiaries of the biomedical and behavioral research enterprise in the United States must motivate linguistic inclusion.

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Section: Underrepresentation Exacerbates Inequitymentioning

confidence: 99%

How Should Representation of Subjects With LEP Become More Equitable in Clinical Trials?

Alhalel

Francone

Post

et al. 2022

AMA Journal of Ethics

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“…As a SDOH, the context of health care and care provision have contributed to racial/ethnic minorities and lower SES groups experiencing lower health care quality, patient experience, and outcomes, as documented in the Institute of Medicine 2003 report, Unequal Treatment [31]. In addition to access and affordability issues, inequities discussed in the report, including implicit racial bias influencing provider attitudes, communication and relationship-building, clinical decisionmaking, and prescribing behaviors, continue to be observed as mechanisms by which these inequities continue [49][50][51].…”

Section: Racial Disparities In Diabetes Prevalence Morbidity and Mort...mentioning

confidence: 99%

Social Determinants of Health, Race, and Diabetes Population Health Improvement: Black/African Americans as a Population Exemplar

et al. 2022

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Purpose of Review To summarize evidence of impact of social determinants of health (SDOH) on diabetes risk, morbidity, and mortality and to illustrate this impact in a population context. Recent Findings Key findings from the American Diabetes Association’s scientific review of five SDOH domains (socioeconomic status, neighborhood and physical environment, food environment, health care, social context) are highlighted. Population-based data on Black/African American adults illustrate persisting diabetes disparities and inequities in the SDOH conditions in which this population is born, grows, lives, and ages, with historical contributors. SDOH recommendations from US national committees largely address a health sector response, including health professional education, SDOH measurement, and patient referral to services for social needs. Fewer recommendations address solutions for systemic racism and socioeconomic discrimination as root causes. Summary SDOH are systemic, population-based, cyclical, and intergenerational, requiring extension beyond health care solutions to multi-sector and multi-policy approaches to achieve future population health improvement.

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“…For example, Black patients with diabetes are less likely to be prescribed the highest quality diabetes medication. 35 Black women diagnosed with endometriosis are less likely to have minimally invasive gynecological surgery. 36 Black and Hispanic women are less likely to receive guideline‐concordant care for gynecologic and breast cancers.…”

Section: Recognizing the Compounding Effects Of Racism And Ableism Fo...mentioning

confidence: 99%

Dobbs and disability: Implications of abortion restrictions for people with chronic health conditions

Hassan

Yates

Hing

et al. 2022

Health Services Research

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Racial/ethnic and socioeconomic disparities in the use of newer diabetes medications in the Look AHEAD study

Cited by 34 publications

References 29 publications

How Should Representation of Subjects With LEP Become More Equitable in Clinical Trials?

How Should Representation of Subjects With LEP Become More Equitable in Clinical Trials?

Social Determinants of Health, Race, and Diabetes Population Health Improvement: Black/African Americans as a Population Exemplar

Dobbs and disability: Implications of abortion restrictions for people with chronic health conditions

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