Racial disparities in the use of SBRT for treating early-stage lung cancer

Impact of Race on Treatment and Survival among U.S. Veterans with Early-Stage Lung Cancer

“…16 Two studies using the National Cancer Data Base found that black patients were less likely to receive stereotactic body radiation therapy and more likely to get standard external beam radiation or no treatment at all, even when the comparison was restricted to inoperable patients. 16,27 We observed no racial differences in survival among the entire cohort, which is similar to the findings of other studies evaluating the correlation between race and overall survival adjusted for covariates in patients with early-stage lung cancer. 14,15,20,28,29 Given the lower percentage of black patients receiving an operation and greater proportion of blacks having other/no treatment, we would have expected disparately worse survival outcomes in black patients.…”

A system‐based intervention to reduce Black‐White disparities in the treatment of early stage lung cancer: A pragmatic trial at five cancer centers

“…When focus is placed on early stage, non‐small cell lung cancer, even when analyses are controlled for important confounders such as age, health insurance, socioeconomic status, and comorbid illness, treatment disadvantages for Black patients remain . The surgical treatment gap has remained since its first recognition decades ago and differences in the use of radiation for cure have come to light as the role for stereotactic radiation in lung cancer cure evolves …”

“…Despite the high mortality and progressive physical limitations that decisions against treatment portend, Black patients undergo surgery less often than similar White patients. Studies spanning decades show persistence of surgical disparities with similar gaps emerging for radiation …”

Lobectomy versus stereotactic body radiotherapy in healthy patients with stage I lung cancer

“…21 The BED 10 was calculated using the linear-quadratic model with an a/b of 10 as described in the radiation literature. 22 A separate analysis was done using BED 10 greater than 130 Gy, because more recent literature has suggested this to be an even more effective dose; this restriction resulted in similar findings (Tables E1 and E2; Figure E2). 9,21,23…”