Racial disparities in overall survival after the introduction of cyclin-dependent kinase 4/6 inhibitors for patients with hormone receptor-positive, HER2 negative metastatic breast cancer
Abstract:Purpose: CDK4/6i combined with endocrine therapy have improved HR+/HER2- metastatic breast cancer (MBC) outcomes. However, it is still unclear whether the response to CDK4/6i is similar for all races. Therefore, we aimed to assess overall survival (OS) trends stratified by race in patients with HR+/HER2- MBC after the approval of CDK4/6i, as part of the standard of care, in 2015.
Methods: We performed a population-based study using the SEER database. Patients with HR+/HER2- MBC were divided into two time-based… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.