Race-Specific Prevalence of Hidradenitis Suppurativa

Sachdeva, Muskaan; Shah, Monica; Alavi, Afsáneh

doi:10.1177/1203475420972348

Cited by 37 publications

(27 citation statements)

References 51 publications

(90 reference statements)

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“…Hidradenitis suppurativa (HS; also known as acne inversa) is a chronically relapsing inflammatory disease with characteristic alterations in skinfolds (1). HS is estimated to affect around 1% of the general population (2)(3)(4), with a common onset in the second and third decade of life (5). The axillary, inguinal, and gluteal areas are most commonly affected.…”

Section: Introductionmentioning

confidence: 99%

Features Associated With Quality of Life Impairment in Hidradenitis Suppurativa Patients

et al. 2021

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Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with an adverse impact on patients' quality of life (QoL).Objectives: To quantify QoL impairment in patients in Germany suffering from HS and to identify the parameters associated with QoL impairment.Methods: A non-interventional, cross-sectional, mono-centric study with 500 HS patients. QoL data (measured using the Dermatology Life Quality Index; DLQI) and demographic, anamnestic, clinical, and blood parameters were collected. All patients were examined by dermatologists that documented the skin alterations. QoL data from 462 HS patients were available and evaluated.Results: The mean (± standard deviation) DLQI score of HS patients was 13.18 ± 7.99. Approximately 40% and 20% of HS patients declared very large and extremely large QoL impairment, respectively. The degree of QoL disturbance correlated with the severity of skin alterations, blood leucocyte count and, in particular, with anogenital localization and the presence of nodules and fistulas. Furthermore, QoL impairment was associated with specific comorbidities, such as adiposity and back pain, but not with HS family history. QoL impairment was not influenced by whether or not the patients had undergone resection surgery or antibiotic treatment but was more severe in HS patients that had undergone abscess lancing compared to patients without such treatment in the past.Limitations: It was a mono-centric study and most data were obtained from self-administered patient questionnaires. The association of QoL with type of treatment was analyzed for abscess lancing, resection surgery, and antibiotic treatment. Further therapeutic modalities recommended in the guidelines were not investigated.Conclusion: A profound impairment in QoL was present in patients with HS, and this was higher than that observed in other studied dermatoses. The degree of impairment correlated with the extent of cutaneous and some extra-cutaneous alterations. Surgical and conventional medicamentous therapies of HS were not associated with long-lasting reduction of QoL impairment. Our data support the implementation of patient-reported outcome measures for the assessment of therapy responses.

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Section: Introductionmentioning

confidence: 99%

Features Associated With Quality of Life Impairment in Hidradenitis Suppurativa Patients

et al. 2021

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“…[20][21][22] Fifth, ethnicity was not reported in our data, potentially limiting our results, as differences in race-specific prevalence of HS, access to healthcare resources and socioeconomic status exist. 23 Finally, recall bias may have affected the quality of our results.…”

Section: Discussionmentioning

confidence: 98%

Patient experiences with hidradenitis suppurativa: the Hidradenitis Patient Experience survey

Kashetsky

Mukovozov

Pereira³

et al. 2021

Clin Experimental Derm

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Summary Background Better understanding of the experience of people living with hidradenitis suppurativa (HS) is essential to identify gaps in current patient care and inform healthcare decision‐making. Aim To describe the patient experience of individuals with HS, including their path to diagnosis, symptom control, treatments, healthcare utilization, patient needs and impact on quality of life. Methods The Hidradenitis Suppurativa Patient Experience survey was created, extensively reviewed and disseminated through engaging HS‐related patient organizations, physician groups and social media groups. Results In total, 537 respondents completed the survey; the mean age was 38 years (range 14–73 years) and 95% (510 of 537) were female. The mean number of treatment types per respondent was 15, and included antibacterial soaps (93.3%; 431 of 462), avoidance of tight clothing (90.9%; 419 of 462), use of oral antibiotics (79.7%; 368 of 462), nonprescription drugs (79.7%; 368 of 462) and topical antibiotics (77.1%; 356 of 262). Pain was poorly controlled in 46% of respondents (184 of 401). HS had a negative impact on the ability to work and attend school for 81% of respondents (337 of 415), with 59% (245 of 415) missing at least 2 days of work a month and 16% (66 of 415) missing > 11 days of work. The mean number of misdiagnoses per respondent was three and the median time to diagnosis was 10 years. Conclusion Individuals with HS experience a delay in diagnosis and have suboptimal control of the disease. We propose 11 recommendations to improve diagnosis, treatment and quality of life for individuals living with HS.

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“…Understanding HS among African American patients in the USA is an ongoing concern 1–5 . A population‐based prevalence of 0.13% 6 and a mean HS incidence of 6.0 per 100 000 person‐years with a 2.5‐fold increase between the years 1968 and 2008 has been reported from Rochester, Minnesota, USA 7 .…”

Section: Epidemiologymentioning

confidence: 99%

Hidradenitis suppurativa in skin of colour

Zouboulis¹,

Goyal

Byrd

2021

Experimental Dermatology

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Hidradenitis suppurativa/acne inversa (HS) more prevalent and disproportionally affects African American females. Although there are limited studies in HS skin of colour populations in the USA, there is more scarcity of HS skin of colour studies in other countries, which limits the overall understanding of the disease among these patients. Herein, our overview of the 10th European Hidradenitis Suppurativa Foundation (EHSF) e.V. Conference provided a crude example of the limited number of skin of colour physicians, physician scientists and inclusion of skin of colour patients highlighting the need to increase awareness of this important issue. We summarized the epidemiology, pathogenesis, clinical picture and focused on treatment options from southeast Asia and Africa. Our outlined general recommendations for diagnosis will render better clinical care and outcomes for diverse patient populations.

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Race-Specific Prevalence of Hidradenitis Suppurativa

Cited by 37 publications

References 51 publications

Features Associated With Quality of Life Impairment in Hidradenitis Suppurativa Patients

Features Associated With Quality of Life Impairment in Hidradenitis Suppurativa Patients

Patient experiences with hidradenitis suppurativa: the Hidradenitis Patient Experience survey

Hidradenitis suppurativa in skin of colour

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