Race as a risk factor in the severity of infragenicular occlusive disease: Study of an urban hospital patient population

Sidawy, Anton N.; Schweitzer, Eugene J.; Neville, Richard F.; Alexander, E.Pendelton; Temeck, Barbara K.; Curry, Kathleen

doi:10.1016/0741-5214(90)90299-p

Cited by 58 publications

(33 citation statements)

References 30 publications

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“…In our series, bypass grafts were reflective of a distal pattern of occlusive disease in HI similar to that in AA, in whom the predilection of arterial disease to the infrageniculate level is well described. 16 The difficulty, both real and perceived, in reconstructing infrageniculate disease may contribute to the inferior results reported in HI with PAD. Lavery et al 6 report that Mexican-American diabetics were four times as likely to have had a failed bypass or to be categorized as "not a bypass candidate" in comparison to non-Hispanic whites.…”

Section: Discussionmentioning

confidence: 99%

Inferior outcomes of autogenous infrainguinal bypass in Hispanics: An analysis of ethnicity, graft function, and limb salvage

Robinson

Owens

Nguyen

et al. 2009

Journal of Vascular Surgery

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Autogenous infrainguinal bypass surgery in HI is associated with primary patency and limb salvage inferior to that of CA and similar to that of AA, despite HI rates of CLI equivalent to CA and HI comorbidities less severe than AA. HI ethnicity was an independent predictor of limb loss. Our data provides evidence of outcome disparities in HI treated aggressively for their PAD. Further investigation with regard to biologic and social factors is required to delineate the reasons for these inferior outcomes in HI patients.

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Section: Discussionmentioning

confidence: 99%

Inferior outcomes of autogenous infrainguinal bypass in Hispanics: An analysis of ethnicity, graft function, and limb salvage

Robinson

Owens

Nguyen

et al. 2009

Journal of Vascular Surgery

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“…29 It is possible that this advanced disease in this distribution may lead to higher incidence of early graft failure in this patient population.…”

Section: Discussionmentioning

confidence: 99%

Factors associated with early failure of infrainguinal lower extremity arterial bypass

Singh

Sidawy

DeZee

et al. 2008

Journal of Vascular Surgery

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“…19 The reason for excess PAD prevalence in blacks is currently unknown. One possibility is higher levels of newer (or novel) risk factors.…”

Section: Discussionmentioning

confidence: 99%

Ethnicity and Peripheral Arterial Disease

et al. 2005

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Background-Previous studies have indicated higher rates of peripheral arterial disease (PAD) in blacks than in non-Hispanic whites (NHWs), with limited information available for Hispanics and Asians. The reason for the PAD excess in blacks is unclear. Methods and Results-Ethnic-specific PAD prevalence rates were determined in a randomly selected defined population that included 4 ethnic groups; NHWs, blacks, Hispanics, and Asians. A total of 2343 participants aged 29 to 91 years were evaluated. There were 104 cases of PAD (4.4%). In weighted logistic models with NHWs as the reference group and containing demographic factors only, blacks had a higher PAD prevalence than NHWs (ORϭ2.30, PϽ0.024), whereas PAD rates in Hispanics and Asians, although somewhat lower, were not significantly different from NHWs. Blacks had significantly more diabetes and hypertension than NHWs and a significantly higher body mass index. Inclusion of these variables and other PAD risk factors in the model did not change the effect size for black ethnicity (ORϭ2.34, Pϭ0.048). A model containing interaction terms for black ethnicity and each of the other risk factors revealed no significant interaction terms, which indicates no evidence that blacks were more "susceptible" than NHWs to cardiovascular disease risk factors. Conclusions-Black ethnicity was a strong and independent risk factor for PAD, which was not explained by higher levels of diabetes, hypertension, and body mass index. There was no evidence of a greater susceptibility of blacks to cardiovascular disease risk factors as a reason for their higher PAD prevalence. Thus, the excess risk of PAD in blacks remains unexplained and requires further study.

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Race as a risk factor in the severity of infragenicular occlusive disease: Study of an urban hospital patient population

Cited by 58 publications

References 30 publications

Inferior outcomes of autogenous infrainguinal bypass in Hispanics: An analysis of ethnicity, graft function, and limb salvage

Inferior outcomes of autogenous infrainguinal bypass in Hispanics: An analysis of ethnicity, graft function, and limb salvage

Factors associated with early failure of infrainguinal lower extremity arterial bypass

Ethnicity and Peripheral Arterial Disease

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