Race and Sex Differences in Age‐Related Hearing Loss: The Health, Aging and Body Composition Study

Helzner, Elizabeth; Cauley, Jane A.; Pratt, Sheila; Wisniewski, Stephen R.; Zmuda, Joseph M.; Talbott, Evelyn O.; Rekeneire, Nathalie de; Harris, Tamara B.; Rubin, Susan M.; Simonsick, Eleanor M.; Tylavsky, Frances A.; Newman, Anne B.

doi:10.1111/j.1532-5415.2005.00525.x

Cited by 286 publications

(290 citation statements)

References 42 publications

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“…[2] According to a study by Helzner, et al it is found to be more common in men than women. [11] In our study also we found majority of patients of older age groups above 65 years.…”

Section: Discussionsupporting

confidence: 59%

Role of Lycopene in Presbycusis

Singh¹

2015

jemds

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Lycopene a red carotenoid found mainly in tomatoes and few other fruits and vegetables, is said to have strong antioxidant properties. This study aims to evaluate the effect of lycopene supplements in patients with age related hearing loss (Presbycusis) and any symptoms related to it like tinnitus. MATERIALS AND METHODSTwo hundred patients with bilateral symmetrical progressive age related sensorineural hearing loss (Presbycusis) were taken up in the study; 100 patients in study group were given capsule supplement containing lycopene and multivitamins once a day after meals for 12 months. Remaining 100 patients in control group were given capsule supplement containing only multivitamins without lycopene once a day after meals for 12 months. Patients were evaluated using Pure Tone Audiometry (PTA) at first visit, after 6 months and after 12 months for degree of hearing loss, tinnitus and any side effects of capsules in both study and control groups. RESULTSThe results showed that presbycusis mainly effects higher speech frequencies (2000 hertz and above). The results showed that there was slower progression of degree of sensorineural hearing loss in study group using lycopene containing supplement as compared to control group without lycopene. There was a marginal improvement in incidence of tinnitus in the study group. There were minimal drug related side effects like nausea, vomiting and diarrhoea with no difference in both groups with or without lycopene. CONCLUSIONSo it can be concluded that Lycopene supplements can be considered as a safe treatment to slower the progress of disease in patients with age related hearing loss.

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“…[2] According to a study by Helzner, et al it is found to be more common in men than women. [11] In our study also we found majority of patients of older age groups above 65 years.…”

Section: Discussionsupporting

confidence: 59%

Role of Lycopene in Presbycusis

Singh¹

2015

jemds

View full text Add to dashboard Cite

show abstract

“…The reason attributed to this phenomenon in an earlier study was due to a higher prevalence of otitis media with effusion and retracted tympanic membranes in the Caucasian group compared to the African group [10]. Furthermore, a study in adults [31] indicated that Caucasians were also more likely to have hearing loss followed by non-Caucasian, black individuals.…”

Section: Discussionmentioning

confidence: 98%

Hearing loss in urban South African school children (grade 1 to 3)

Mahomed-Asmail

Swanepoel

Eikelboom

2016

International Journal of Pediatric Otorhinolaryngology

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“…Previous reports from large epidemiological studies (Cooper 1994;Helzner et al 2005;Agrawal et al 2008;Lin et al 2011a, b) and from smaller case-control studies of workers with occupational noise exposure (Jerger et al 1986;Ishii and Talbott 1998) have consistently demonstrated better hearing thresholds in black compared with white participants. A number of explanatory factors may be theoretically implicated to explain the observed association between race and hearing loss in these studies.…”

Section: Potential Mechanistic Pathwaysmentioning

confidence: 99%

“…Epidemiologic studies of large population-based cohorts have consistently demonstrated lower rates of hearing loss among black than white participants with the odds of hearing loss generally 40-60% lower in black individuals (Cooper 1994;Helzner et al 2005;Lin et al 2011b). These findings have also been corroborated in smaller epidemiological studies that have investigated rates of hearing loss in workers exposed to similar levels of occupational noise.…”

Section: Introductionmentioning

confidence: 99%

Association of Skin Color, Race/Ethnicity, and Hearing Loss Among Adults in the USA

Lin

Maas

Chien

et al. 2011

JARO

110

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Epidemiologic studies of hearing loss in adults have demonstrated that the odds of hearing loss are substantially lower in black than in white individuals. The basis of this association is unknown. We hypothesized that skin pigmentation as a marker of melanocytic functioning mediates this observed association and that skin pigmentation is associated with hearing loss independent of race/ethnicity. We analyzed cross-sectional data from 1,258 adults (20-59 years) in the 2003-2004 cycle of the National Health and Nutritional Examination Survey who had assessment of Fitzpatrick skin type and pure-tone audiometric testing. Audiometric thresholds in the worse hearing ear were used to calculate speech-(0.5-4 kHz) and high-frequency (3-8 kHz) pure-tone averages (PTA). Regression models were stratified by Fitzpatrick skin type or race/ethnicity to examine the association of each factor with hearing loss independent of the other. Models were adjusted for potential confounders (demographic, medical, and noise exposure covariates). Among all participants, race/ethnicity was associated with hearing thresholds (black participants with the best hearing followed by Hispanics and then white individuals), but these associations were not significant in analyses stratified by skin color. In contrast, in race-stratified analyses, darker-skinned Hispanics had better hearing than lighterskinned Hispanics by an average of −2.5 dB hearing level (HL; 95% CI, −4.8 to −0.2) and −3.1 dB HL (95% CI, −5.3 to −0.8) for speech and high-frequency PTA, respectively. Associations between skin color and hearing loss were not significant in white and black participants. Our results demonstrate that skin pigmentation is independently associated with hearing loss in Hispanics and suggest that skin pigmentation as a marker of melanocytic functioning may mediate the strong association observed between race/ethnicity and hearing loss.

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Race and Sex Differences in Age‐Related Hearing Loss: The Health, Aging and Body Composition Study

Abstract: Hearing loss was extremely common in this population. Because many of the identified hearing loss risk factors are modifiable, some of the burden associated with hearing loss in older people should be preventable.

Cited by 286 publications

References 42 publications

Role of Lycopene in Presbycusis

Role of Lycopene in Presbycusis

Hearing loss in urban South African school children (grade 1 to 3)

Association of Skin Color, Race/Ethnicity, and Hearing Loss Among Adults in the USA

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