Rabies, a Vaccine Preventable Disease: Current Status, Epidemiology, Pathogenesis, Prevention and Control With Special Reference to India

Singh, Vikram; Singh, KK; Saminathan, Mani; Vineetha, S.; Reddy, G.B. Manjunatha; Maity, Madhulina; Cherian, Susan; Dhama, Kuldeep

doi:10.18006/2018.6(1).62.86

Cited by 10 publications

(5 citation statements)

References 72 publications

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“…This may also lead to disproportionate deviation from the PEP guidelines. (19,20).The staff from the Hospital Infection Control clarified all the queries raised by HCWs in an objective and timely manner. In addition to this, they also provided comprehensive education regarding the risks of rabies transmission and the use of PEP for all those HCWs and the laboratory staff who were considered as high risk exposures.…”

Section: Resultsmentioning

confidence: 99%

Risk Assessment and Recommendation of Post Exposure Prophylaxis after a Sentinel Case of Rabies in a Tertiary Care Hospital, South India

Madigubba¹,

ika²,

Dhodapkar³

et al. 2019

Int.J.Curr.Microbiol.App.Sci

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Section: Resultsmentioning

confidence: 99%

Risk Assessment and Recommendation of Post Exposure Prophylaxis after a Sentinel Case of Rabies in a Tertiary Care Hospital, South India

Madigubba¹,

ika²,

Dhodapkar³

et al. 2019

Int.J.Curr.Microbiol.App.Sci

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“…In addition, our findings confirm that statistically significant clusters of foxes preceded in time the clusters of all other species. However, more robust observational and genetic studies should be implemented to prove the interspecies transmission (34).…”

Section: Discussionmentioning

confidence: 99%

An Analysis of Rabies Incidence and Its Geographic Spread in the Buffer Area Among Orally Vaccinated Wildlife in Ukraine From 2012 to 2016

Polupan¹,

Bezymennyi

Gibaliuk

et al. 2019

Front. Vet. Sci.

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The statistics of rabies cases in Volyn, Lviv, and Zakarpattia oblasts of Ukraine from 2012 to 2016 were analyzed to establish spatial–temporal distribution of rabies endemic outbreaks and to identify causes of widespread infections among wild and domestic animals. The occurrence of rabies outbreaks in wild and domestic animals in Ukraine was also assessed to determine the effectiveness of oral rabies vaccination (ORV) efforts. According to our analysis, parenteral vaccination of domestic animals and ORV campaigns in foxes have proved unsuccessful in providing a sustainable, long-term reduction in endemic rabies outbreaks. ORV campaigns in foxes were deemed ineffective based on our studies of the endemic rabies outbreaks in Volyn, Lviv, and Zakarpattia oblasts in 2012–2016. The current rabies prevention system (parenteral vaccination) failed to offer protection to domestic animals based on our review of the occurrence of endemic rabies outbreaks in dogs and cats. ORV campaign shortcomings and their causes must be identified in order to provide maximum rabies vaccine coverage for dogs and cats. Altogether, the results presented here provide information that can assist public health agencies to devise more effective disease control plans to curtail the spread of rabies in domestic animals and wildlife in Ukraine.

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“…There exist a minimum of 14 distinct Lyssavirus species, categorized into 2 phylogroups according to genetic variance and serological cross-response (30). According to the World Health Organization (WHO), Asia witnesses about 30,000 RABV-related deaths each year (31). Over 3 billion people in Asia are exposed to dog rabies, resulting in an Asian death every 15 minutes, with children under 15 years constituting around 15% of these casualties (32, 33, and 34).…”

Section: Figure 1: Etiology Of Rabies Virusmentioning

confidence: 99%

Guarding Against Rabies: The Power of Vaccination in Rabies Disease Management

Javed

2023

jwmdc

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Rabies, a lethal viral disease caused by the rabies virus, presents a critical public health challenge globally. The disease's etiology involves transmission through the bite or scratch of infected animals, primarily dogs, with the virus targeting the central nervous system and leading to devastating neurological symptoms. Early diagnosis is crucial but challenging due to the disease's non-specific initial manifestations. Vaccination strategies serve as the cornerstone of rabies prevention, encompassing pre-exposure prophylaxis for high-risk individuals and post-exposure prophylaxis for those bitten or scratched by potentially rabid animals. In this article we provide an in-depth exploration of vaccination therapy as a pivotal strategy in the deterrence and management of rabies. The evolution of rabies vaccines, particularly inactivated virus vaccines, is explored, underscoring their role in reducing human rabies cases. The article concludes by emphasizing the significance of continuous research to enhance vaccine effectiveness and promote a comprehensive approach to rabies prevention.

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Rabies, a Vaccine Preventable Disease: Current Status, Epidemiology, Pathogenesis, Prevention and Control With Special Reference to India

Cited by 10 publications

References 72 publications

Risk Assessment and Recommendation of Post Exposure Prophylaxis after a Sentinel Case of Rabies in a Tertiary Care Hospital, South India

Risk Assessment and Recommendation of Post Exposure Prophylaxis after a Sentinel Case of Rabies in a Tertiary Care Hospital, South India

An Analysis of Rabies Incidence and Its Geographic Spread in the Buffer Area Among Orally Vaccinated Wildlife in Ukraine From 2012 to 2016

Guarding Against Rabies: The Power of Vaccination in Rabies Disease Management

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